Category:GO:0004642 ! phosphoribosylformylglycinamidine synthase activity

name: phosphoribosylformylglycinamidine synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate." [EC:6.3.5.3, RHEA:17132]
subset: gosubset_prok
synonym: "2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3]
synonym: "5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3]
synonym: "FGAM synthase activity" EXACT [EC:6.3.5.3]
synonym: "FGAM synthetase activity" EXACT [EC:6.3.5.3]
synonym: "FGAR amidotransferase activity" EXACT [EC:6.3.5.3]
synonym: "FGARAT activity" EXACT [EC:6.3.5.3]
synonym: "formylglycinamide ribonucloetide amidotransferase activity" EXACT [EC:6.3.5.3]
synonym: "formylglycinamide ribotide amidotransferase activity" EXACT [EC:6.3.5.3]
synonym: "N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)" EXACT [EC:6.3.5.3]
synonym: "phosphoribosylformylglycinamidine synthetase activity" EXACT [EC:6.3.5.3]
synonym: "phosphoribosylformylglycineamidine synthetase activity" EXACT [EC:6.3.5.3]
xref: EC:6.3.5.3
xref: KEGG:R04463
xref: MetaCyc:FGAMSYN-RXN
xref: Reactome:REACT_100090 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Schizosaccharomyces pombe"
xref: Reactome:REACT_103088 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Drosophila melanogaster"
xref: Reactome:REACT_107579 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Bos taurus"
xref: Reactome:REACT_108774 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Saccharomyces cerevisiae"
xref: Reactome:REACT_110503 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Arabidopsis thaliana"
xref: Reactome:REACT_112941 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Xenopus tropicalis"
xref: Reactome:REACT_115636 "5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate, Gallus gallus"
xref: Reactome:REACT_1427 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Homo sapiens"
xref: Reactome:REACT_80286 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Escherichia coli"
xref: Reactome:REACT_80793 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Caenorhabditis elegans"
xref: Reactome:REACT_87595 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Danio rerio"
xref: Reactome:REACT_88114 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Taeniopygia guttata"
xref: Reactome:REACT_92684 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Rattus norvegicus"
xref: Reactome:REACT_97086 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Mus musculus"
xref: Reactome:REACT_97309 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Dictyostelium discoideum"
xref: Reactome:REACT_97565 "FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi, Canis familiaris"
xref: RHEA:17132
is_a: GO:0016884 ! carbon-nitrogen ligase activity, with glutamine as amido-N-donor

AmiGO

Pages in category "GO:0004642 ! phosphoribosylformylglycinamidine synthase activity"

The following 11 pages are in this category, out of 11 total.