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Category:GO:0004525 ! ribonuclease III activity
name: ribonuclease III activity
namespace: molecular_function
def: "Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt." [PMID:11157775, PMID:15242644]
synonym: "pre-mRNA 3'-end processing endonuclease" NARROW []
synonym: "ribonuclease 3 activity" RELATED [EC:3.1.26.3]
synonym: "RNase III activity" RELATED [EC:3.1.26.3]
xref: EC:3.1.26.3
xref: MetaCyc:3.1.26.3-RXN
is_a: GO:0016891 ! RNA endonuclease activity, producing 5'-phosphomonoesters
is_a: GO:0032296 ! double-stranded RNA-specific ribonuclease activity
AmiGO
<GOterm>GO:0004525</GOterm>
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