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Category:GO:0004502 ! kynurenine 3-monooxygenase activity
name: kynurenine 3-monooxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+)." [EC:1.14.13.9, RHEA:20548]
subset: gosubset_prok
synonym: "kynurenine 3-hydroxylase activity" EXACT []
synonym: "kynurenine hydroxylase activity" EXACT [EC:1.14.13.9]
synonym: "L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)" EXACT [EC:1.14.13.9]
synonym: "L-kynurenine-3-hydroxylase activity" EXACT [EC:1.14.13.9]
xref: EC:1.14.13.9
xref: KEGG:R01960
xref: MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN
xref: Reactome:REACT_100337 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Mus musculus"
xref: Reactome:REACT_100740 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Caenorhabditis elegans"
xref: Reactome:REACT_108549 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Bos taurus"
xref: Reactome:REACT_109130 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Danio rerio"
xref: Reactome:REACT_79840 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Dictyostelium discoideum"
xref: Reactome:REACT_79885 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Taeniopygia guttata"
xref: Reactome:REACT_82021 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Rattus norvegicus"
xref: Reactome:REACT_84641 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Saccharomyces cerevisiae"
xref: Reactome:REACT_86351 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Xenopus tropicalis"
xref: Reactome:REACT_90028 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Canis familiaris"
xref: Reactome:REACT_927 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Homo sapiens"
xref: Reactome:REACT_96923 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Drosophila melanogaster"
xref: Reactome:REACT_98896 "kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O, Gallus gallus"
xref: RHEA:20548
is_a: GO:0016709 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
AmiGO
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