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Category:GO:0004463 ! leukotriene-A4 hydrolase activity
name: leukotriene-A4 hydrolase activity
namespace: molecular_function
def: "Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4)." [EC:3.3.2.6, RHEA:22327]
subset: gosubset_prok
synonym: "(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity" EXACT [EC:3.3.2.6]
synonym: "leukotriene A(4) hydrolase activity" EXACT [EC:3.3.2.6]
synonym: "leukotriene A4 hydrolase activity" EXACT [EC:3.3.2.6]
synonym: "LTA-4 hydrolase activity" EXACT [EC:3.3.2.6]
synonym: "LTA4 hydrolase activity" EXACT [EC:3.3.2.6]
synonym: "LTA4H" RELATED [EC:3.3.2.6]
xref: EC:3.3.2.6
xref: KEGG:R03057
xref: MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN
xref: Reactome:REACT_107223 "LTA4 is hydrolyzed to LTB4, Mus musculus"
xref: Reactome:REACT_113583 "LTA4 is hydrolyzed to LTB4, Dictyostelium discoideum"
xref: Reactome:REACT_113737 "LTA4 is hydrolyzed to LTB4, Mycobacterium tuberculosis"
xref: Reactome:REACT_115125 "LTA4 is hydrolyzed to LTB4, Saccharomyces cerevisiae"
xref: Reactome:REACT_115164 "LTA4 is hydrolyzed to LTB4, Schizosaccharomyces pombe"
xref: Reactome:REACT_15478 "LTA4 is hydrolyzed to LTB4, Homo sapiens"
xref: Reactome:REACT_28633 "LTA4 is hydrolyzed to LTB4, Drosophila melanogaster"
xref: Reactome:REACT_80031 "LTA4 is hydrolyzed to LTB4, Canis familiaris"
xref: Reactome:REACT_82629 "LTA4 is hydrolyzed to LTB4, Caenorhabditis elegans"
xref: Reactome:REACT_83037 "LTA4 is hydrolyzed to LTB4, Rattus norvegicus"
xref: Reactome:REACT_87303 "LTA4 is hydrolyzed to LTB4, Xenopus tropicalis"
xref: Reactome:REACT_91502 "LTA4 is hydrolyzed to LTB4, Bos taurus"
xref: Reactome:REACT_92157 "LTA4 is hydrolyzed to LTB4, Taeniopygia guttata"
xref: Reactome:REACT_93154 "LTA4 is hydrolyzed to LTB4, Danio rerio"
xref: Reactome:REACT_94702 "LTA4 is hydrolyzed to LTB4, Gallus gallus"
xref: Reactome:REACT_98948 "LTA4 is hydrolyzed to LTB4, Sus scrofa"
xref: RHEA:22327
is_a: GO:0016803 ! ether hydrolase activity
AmiGO
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