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Category:GO:0004419 ! hydroxymethylglutaryl-CoA lyase activity
name: hydroxymethylglutaryl-CoA lyase activity
namespace: molecular_function
def: "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA." [EC:4.1.3.4, RHEA:24407]
subset: gosubset_prok
synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)" EXACT [EC:4.1.3.4]
synonym: "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity" EXACT [EC:4.1.3.4]
synonym: "3-hydroxy-3-methylglutarate-CoA lyase activity" EXACT [EC:4.1.3.4]
synonym: "3-hydroxy-3-methylglutaryl CoA cleaving enzyme" RELATED [EC:4.1.3.4]
synonym: "3-hydroxy-3-methylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4]
synonym: "3-hydroxy-3-methylglutaryl-CoA lyase activity" EXACT [EC:4.1.3.4]
synonym: "HMG-CoA lyase activity" EXACT [EC:4.1.3.4]
synonym: "hydroxymethylglutaryl coenzyme A lyase activity" EXACT [EC:4.1.3.4]
synonym: "hydroxymethylglutaryl coenzyme A-cleaving enzyme" RELATED [EC:4.1.3.4]
xref: EC:4.1.3.4
xref: KEGG:R01360
xref: MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN
xref: Reactome:REACT_100202 "HMG CoA => acetoacetic acid + acetyl CoA, Dictyostelium discoideum"
xref: Reactome:REACT_104457 "HMG CoA => acetoacetic acid + acetyl CoA, Drosophila melanogaster"
xref: Reactome:REACT_105243 "HMG CoA => acetoacetic acid + acetyl CoA, Canis familiaris"
xref: Reactome:REACT_108952 "HMG CoA => acetoacetic acid + acetyl CoA, Gallus gallus"
xref: Reactome:REACT_110966 "HMG CoA => acetoacetic acid + acetyl CoA, Arabidopsis thaliana"
xref: Reactome:REACT_2103 "HMG CoA => acetoacetic acid + acetyl CoA, Homo sapiens"
xref: Reactome:REACT_29720 "HMG CoA => acetoacetic acid + acetyl CoA, Oryza sativa"
xref: Reactome:REACT_31175 "HMG CoA => acetoacetic acid + acetyl CoA, Taeniopygia guttata"
xref: Reactome:REACT_86954 "HMG CoA => acetoacetic acid + acetyl CoA, Mus musculus"
xref: Reactome:REACT_89460 "HMG CoA => acetoacetic acid + acetyl CoA, Xenopus tropicalis"
xref: Reactome:REACT_90800 "HMG CoA => acetoacetic acid + acetyl CoA, Rattus norvegicus"
xref: Reactome:REACT_91737 "HMG CoA => acetoacetic acid + acetyl CoA, Bos taurus"
xref: Reactome:REACT_99837 "HMG CoA => acetoacetic acid + acetyl CoA, Danio rerio"
xref: Reactome:REACT_99898 "HMG CoA => acetoacetic acid + acetyl CoA, Caenorhabditis elegans"
xref: RHEA:24407
is_a: GO:0016833 ! oxo-acid-lyase activity
AmiGO
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Pages in category "GO:0004419 ! hydroxymethylglutaryl-CoA lyase activity"
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