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Category:GO:0004383 ! guanylate cyclase activity
name: guanylate cyclase activity
namespace: molecular_function
def: "Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate." [EC:4.6.1.2]
subset: gosubset_prok
synonym: "GTP diphosphate-lyase (cyclizing) activity" EXACT [EC:4.6.1.2]
synonym: "GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity" EXACT [EC:4.6.1.2]
synonym: "guanyl cyclase activity" EXACT [EC:4.6.1.2]
synonym: "guanylyl cyclase activity" EXACT []
synonym: "receptor guanylate cyclase activity" NARROW []
xref: EC:4.6.1.2
xref: MetaCyc:GUANYLCYC-RXN
xref: Reactome:REACT_108080 "Soluble guanylate cyclase converts GTP to cGMP, Sus scrofa"
xref: Reactome:REACT_115231 "Soluble guanylate cyclase converts GTP to cGMP, Dictyostelium discoideum"
xref: Reactome:REACT_115362 "Soluble guanylate cyclase converts GTP to cGMP, Mycobacterium tuberculosis"
xref: Reactome:REACT_23790 "Soluble guanylate cyclase converts GTP to cGMP, Homo sapiens"
xref: Reactome:REACT_23978 "Soluble guanylate cyclase converts GTP to cGMP, Rattus norvegicus"
xref: Reactome:REACT_29218 "Soluble guanylate cyclase converts GTP to cGMP, Bos taurus"
xref: Reactome:REACT_30126 "Soluble guanylate cyclase converts GTP to cGMP, Drosophila melanogaster"
xref: Reactome:REACT_31354 "Soluble guanylate cyclase converts GTP to cGMP, Mus musculus"
xref: Reactome:REACT_32985 "Soluble guanylate cyclase converts GTP to cGMP, Xenopus tropicalis"
xref: Reactome:REACT_83069 "Soluble guanylate cyclase converts GTP to cGMP, Danio rerio"
xref: Reactome:REACT_85642 "Soluble guanylate cyclase converts GTP to cGMP, Taeniopygia guttata"
xref: Reactome:REACT_90434 "Soluble guanylate cyclase converts GTP to cGMP, Gallus gallus"
xref: Reactome:REACT_96120 "Soluble guanylate cyclase converts GTP to cGMP, Canis familiaris"
xref: RHEA:13668
is_a: GO:0009975 ! cyclase activity
is_a: GO:0016849 ! phosphorus-oxygen lyase activity
AmiGO
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Pages in category "GO:0004383 ! guanylate cyclase activity"
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