The Spring 2012 season of CACAO has started!
Category:GO:0004300 ! enoyl-CoA hydratase activity
name: enoyl-CoA hydratase activity
namespace: molecular_function
alt_id:GO:0016510
def: "Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O." [EC:4.2.1.17]
subset: gosubset_prok
synonym: "(3S)-3-hydroxyacyl-CoA hydro-lyase activity" EXACT [EC:4.2.1.17]
synonym: "2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17]
synonym: "2-octenoyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17]
synonym: "acyl coenzyme A hydrase activity" EXACT [EC:4.2.1.17]
synonym: "beta-hydroxyacid dehydrase activity" EXACT [EC:4.2.1.17]
synonym: "beta-hydroxyacyl-CoA dehydrase activity" EXACT [EC:4.2.1.17]
synonym: "crotonyl hydrase activity" EXACT [EC:4.2.1.17]
synonym: "D-3-hydroxyacyl-CoA dehydratase" BROAD [EC:4.2.1.17]
synonym: "ECH" RELATED [EC:4.2.1.17]
synonym: "enol-CoA hydratase activity" EXACT [EC:4.2.1.17]
synonym: "enoyl coenzyme A hydrase (D)" BROAD [EC:4.2.1.17]
synonym: "enoyl coenzyme A hydrase (L)" EXACT [EC:4.2.1.17]
synonym: "enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17]
synonym: "enoyl hydrase activity" EXACT [EC:4.2.1.17]
synonym: "hydratase, enoyl coenzyme A" EXACT [EC:4.2.1.17]
synonym: "short chain enoyl coenzyme A hydratase activity" EXACT [EC:4.2.1.17]
synonym: "short-chain enoyl-CoA hydratase activity" EXACT []
synonym: "trans-2-enoyl-CoA hydratase activity" EXACT [EC:4.2.1.17]
synonym: "unsaturated acyl-CoA hydratase activity" EXACT [EC:4.2.1.17]
xref: EC:4.2.1.17
xref: MetaCyc:ENOYL-COA-HYDRAT-RXN
xref: Reactome:REACT_100244 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Escherichia coli"
xref: Reactome:REACT_101009 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_102396 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Canis familiaris"
xref: Reactome:REACT_103471 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_103986 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_104078 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_104151 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Escherichia coli"
xref: Reactome:REACT_104418 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_104448 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_105085 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_105300 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Sus scrofa"
xref: Reactome:REACT_105444 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Escherichia coli"
xref: Reactome:REACT_105604 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_106492 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_106863 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_107470 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Gallus gallus"
xref: Reactome:REACT_107615 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Danio rerio"
xref: Reactome:REACT_107774 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_107955 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Bos taurus"
xref: Reactome:REACT_1081 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_108453 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_109 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_109467 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Danio rerio"
xref: Reactome:REACT_110285 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_110603 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Canis familiaris"
xref: Reactome:REACT_110864 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_1513 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_1582 "tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA, Homo sapiens"
xref: Reactome:REACT_2238 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Homo sapiens"
xref: Reactome:REACT_28724 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_28770 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Escherichia coli"
xref: Reactome:REACT_29458 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Danio rerio"
xref: Reactome:REACT_297 "methacrylyl-CoA + H2O <=> beta-hydroxyisobutyryl-CoA, Homo sapiens"
xref: Reactome:REACT_31820 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_32105 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_32676 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_32695 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Danio rerio"
xref: Reactome:REACT_32816 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_32949 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_33031 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Sus scrofa"
xref: Reactome:REACT_33248 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_33368 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_33412 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Canis familiaris"
xref: Reactome:REACT_33601 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Danio rerio"
xref: Reactome:REACT_33795 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_34057 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_34615 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Dictyostelium discoideum"
xref: Reactome:REACT_34665 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_386 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_440 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Homo sapiens"
xref: Reactome:REACT_45972 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Bos taurus"
xref: Reactome:REACT_52162 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Bos taurus"
xref: Reactome:REACT_583 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_64 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_65800 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Dictyostelium discoideum"
xref: Reactome:REACT_77114 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_77283 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Danio rerio"
xref: Reactome:REACT_78294 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_78515 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_78642 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Bos taurus"
xref: Reactome:REACT_79462 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_79591 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Danio rerio"
xref: Reactome:REACT_80706 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_80753 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Drosophila melanogaster"
xref: Reactome:REACT_81483 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Mus musculus"
xref: Reactome:REACT_82337 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Mus musculus"
xref: Reactome:REACT_82344 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Canis familiaris"
xref: Reactome:REACT_83439 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Canis familiaris"
xref: Reactome:REACT_83846 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_84610 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_86074 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_86077 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Gallus gallus"
xref: Reactome:REACT_86167 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Mus musculus"
xref: Reactome:REACT_86330 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Mus musculus"
xref: Reactome:REACT_86441 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_86568 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Mus musculus"
xref: Reactome:REACT_87 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Homo sapiens"
xref: Reactome:REACT_87006 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Bos taurus"
xref: Reactome:REACT_87419 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_87516 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_87919 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_88425 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Dictyostelium discoideum"
xref: Reactome:REACT_88762 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_89046 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_89107 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_89468 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Mus musculus"
xref: Reactome:REACT_90188 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_90658 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_90749 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_91036 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_91290 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_91308 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Gallus gallus"
xref: Reactome:REACT_92305 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Danio rerio"
xref: Reactome:REACT_92484 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Escherichia coli"
xref: Reactome:REACT_92535 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_92611 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Sus scrofa"
xref: Reactome:REACT_92945 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Bos taurus"
xref: Reactome:REACT_93500 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Bos taurus"
xref: Reactome:REACT_93874 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_94005 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Bos taurus"
xref: Reactome:REACT_94035 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Dictyostelium discoideum"
xref: Reactome:REACT_94076 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_94548 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Gallus gallus"
xref: Reactome:REACT_95213 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Caenorhabditis elegans"
xref: Reactome:REACT_95378 "Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA, Xenopus tropicalis"
xref: Reactome:REACT_95590 "trans-Hexadec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxyhexadecanoyl-CoA, Rattus norvegicus"
xref: Reactome:REACT_95627 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Danio rerio"
xref: Reactome:REACT_95883 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_97155 "trans-Tetradec-2-enoyl-CoA+H2O<=>(S)-3-Hydroxytetradecanoyl-CoA, Taeniopygia guttata"
xref: Reactome:REACT_97360 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Mus musculus"
xref: Reactome:REACT_97546 "trans-Hex-2-enoyl-CoA+H2O<=>(S)-Hydroxyhexanoyl-CoA, Mus musculus"
xref: Reactome:REACT_97757 "trans-Oct-2-enoyl-CoA+H2O<=>(S)-Hydroxyoctanoyl-CoA, Dictyostelium discoideum"
xref: Reactome:REACT_98369 "2-trans-Dodecenoyl-CoA+H2O<=>(S)-3-Hydroxydodecanoyl-CoA, Mycobacterium tuberculosis"
xref: Reactome:REACT_99625 "trans-Dec-2-enoyl-CoA+H2O<=>(S)-Hydroxydecanoyl-CoA, Mus musculus"
xref: Reactome:REACT_99776 "Removal of six carbons from Linoleoyl-CoA to form cis,cis-3,6- Dodecadienoyl-CoA, Bos taurus"
xref: Reactome:REACT_99997 "Crotonoyl-CoA+H2O<=>(S)-3-Hydroxybutanoyl-CoA, Sus scrofa"
xref: RHEA:16108
xref: UM-BBD_enzymeID:e0014
is_a: GO:0016836 ! hydro-lyase activity
AmiGO
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