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Category:GO:0004298 ! threonine-type endopeptidase activity
name: threonine-type endopeptidase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]
synonym: "26S protease" RELATED [EC:3.4.25.-]
synonym: "alkaline protease" RELATED [EC:3.4.25.-]
synonym: "ingensin" RELATED [EC:3.4.25.-]
synonym: "large multicatalytic protease" NARROW [EC:3.4.25.-]
synonym: "lens neutral proteinase" NARROW [EC:3.4.25.-]
synonym: "MCP" RELATED [EC:3.4.25.-]
synonym: "multicatalytic endopeptidase complex" RELATED [EC:3.4.25.-]
synonym: "multicatalytic proteinase" NARROW [EC:3.4.25.-]
synonym: "multicatalytic proteinase (complex)" NARROW [EC:3.4.25.-]
synonym: "prosome" RELATED [EC:3.4.25.-]
synonym: "proteasome endopeptidase complex" NARROW [EC:3.4.25.-]
synonym: "threonine endopeptidase activity" EXACT []
synonym: "tricorn protease" NARROW [EC:3.4.25.-]
synonym: "tricorn proteinase" NARROW [EC:3.4.25.-]
xref: EC:3.4.25.-
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0070003 ! threonine-type peptidase activity
AmiGO
<GOterm>GO:0004298</GOterm>
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