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Category:GO:0004129 ! cytochrome-c oxidase activity
name: cytochrome-c oxidase activity
namespace: molecular_function
def: "Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O." [EC:1.9.3.1]
comment: The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
subset: gosubset_prok
synonym: "aa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1]
synonym: "ba3-type cytochrome c oxidase" NARROW [EC:1.9.3.1]
synonym: "caa3-type cytochrome c oxidase" NARROW [EC:1.9.3.1]
synonym: "cbb3-type cytochrome c oxidase" NARROW [EC:1.9.3.1]
synonym: "complex IV (mitochondrial electron transport) activity" RELATED [EC:1.9.3.1]
synonym: "cytochrome a3 activity" NARROW [EC:1.9.3.1]
synonym: "cytochrome aa3 activity" NARROW [EC:1.9.3.1]
synonym: "cytochrome oxidase activity" RELATED [EC:1.9.3.1]
synonym: "ferrocytochrome c oxidase" NARROW [EC:1.9.3.1]
synonym: "ferrocytochrome-c:oxygen oxidoreductase" NARROW [EC:1.9.3.1]
synonym: "indophenol oxidase" NARROW [EC:1.9.3.1]
synonym: "indophenolase" NARROW [EC:1.9.3.1]
synonym: "NADH cytochrome c oxidase" EXACT [EC:1.9.3.1]
synonym: "warburg's respiratory enzyme activity" RELATED [EC:1.9.3.1]
xref: EC:1.9.3.1
xref: MetaCyc:CYTOCHROME-C-OXIDASE-RXN
xref: Reactome:REACT_113276 "Electron transfer from reduced cytochrome c to molecular oxygen, Bos taurus"
xref: Reactome:REACT_113311 "Electron transfer from reduced cytochrome c to molecular oxygen, Sus scrofa"
xref: Reactome:REACT_113736 "Electron transfer from reduced cytochrome c to molecular oxygen, Canis familiaris"
xref: Reactome:REACT_115027 "Electron transfer from reduced cytochrome c to molecular oxygen, Rattus norvegicus"
xref: Reactome:REACT_33608 "Electron transfer from reduced cytochrome c to molecular oxygen, Danio rerio"
xref: Reactome:REACT_6149 "Electron transfer from reduced cytochrome c to molecular oxygen, Homo sapiens"
xref: Reactome:REACT_78871 "Electron transfer from reduced cytochrome c to molecular oxygen, Gallus gallus"
xref: Reactome:REACT_99789 "Electron transfer from reduced cytochrome c to molecular oxygen, Mus musculus"
is_a: GO:0015002 ! heme-copper terminal oxidase activity
is_a: GO:0015078 ! hydrogen ion transmembrane transporter activity
is_a: GO:0016676 ! oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AmiGO
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Pages in category "GO:0004129 ! cytochrome-c oxidase activity"
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