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Category:GO:0004087 ! carbamoyl-phosphate synthase (ammonia) activity
name: carbamoyl-phosphate synthase (ammonia) activity
namespace: molecular_function
def: "Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate." [EC:6.3.4.16, RHEA:10627]
subset: gosubset_prok
synonym: "carbamoyl phosphate synthase (ammonia) activity" EXACT []
synonym: "carbamoyl-phosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16]
synonym: "carbamoyl-phosphate synthetase I activity" EXACT [EC:6.3.4.16]
synonym: "carbamoylphosphate synthase (ammonia)" EXACT [EC:6.3.4.16]
synonym: "carbamoylphosphate synthase activity" EXACT [EC:6.3.4.16]
synonym: "carbamoylphosphate synthetase (ammonia) activity" EXACT [EC:6.3.4.16]
synonym: "carbamylphosphate synthetase activity" EXACT [EC:6.3.4.16]
synonym: "carbamylphosphate synthetase I" RELATED [EC:6.3.4.16]
synonym: "carbmoylphosphate synthetase activity" EXACT [EC:6.3.4.16]
synonym: "carbon-dioxide--ammonia ligase activity" EXACT [EC:6.3.4.16]
synonym: "carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)" EXACT [EC:6.3.4.16]
synonym: "CPS I activity" NARROW [EC:6.3.4.16]
xref: EC:6.3.4.16
xref: KEGG:R00149
xref: MetaCyc:6.3.4.16-RXN
xref: Reactome:REACT_104425 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Bos taurus"
xref: Reactome:REACT_112052 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Plasmodium falciparum"
xref: Reactome:REACT_112191 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Saccharomyces cerevisiae"
xref: Reactome:REACT_112781 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Schizosaccharomyces pombe"
xref: Reactome:REACT_1701 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Homo sapiens"
xref: Reactome:REACT_28657 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Gallus gallus"
xref: Reactome:REACT_32408 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Staphylococcus aureus N315"
xref: Reactome:REACT_32830 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Taeniopygia guttata"
xref: Reactome:REACT_45108 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Mus musculus"
xref: Reactome:REACT_78285 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Xenopus tropicalis"
xref: Reactome:REACT_79612 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Danio rerio"
xref: Reactome:REACT_81920 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Sus scrofa"
xref: Reactome:REACT_87223 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Canis familiaris"
xref: Reactome:REACT_89630 "2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial], Rattus norvegicus"
xref: RHEA:10627
is_a: GO:0016879 ! ligase activity, forming carbon-nitrogen bonds
AmiGO
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