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Category:GO:0004052 ! arachidonate 12(S)-lipoxygenase activity
name: arachidonate 12(S)-lipoxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate." [EC:1.13.11.31, RHEA:10428]
synonym: "12-lipoxygenase activity" RELATED [EC:1.13.11.31]
synonym: "12Delta-lipoxygenase activity" RELATED [EC:1.13.11.31]
synonym: "12S-lipoxygenase activity" RELATED [EC:1.13.11.31]
synonym: "arachidonate:oxygen 12-oxidoreductase activity" RELATED [EC:1.13.11.31]
synonym: "C-12 lipoxygenase activity" RELATED [EC:1.13.11.31]
synonym: "delta12-lipoxygenase activity" RELATED [EC:1.13.11.31]
synonym: "leukotriene A4 synthase" BROAD [EC:1.13.11.31]
synonym: "LTA4 synthase activity" RELATED [EC:1.13.11.31]
xref: EC:1.13.11.31
xref: KEGG_REACTION:R01596
xref: MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN
xref: RHEA:10428
is_a: GO:0016702 ! oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AmiGO
<GOterm>GO:0004052</GOterm>
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