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Category:GO:0003923 ! GPI-anchor transamidase activity
name: GPI-anchor transamidase activity
namespace: molecular_function
def: "Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor." [ISBN:0471331309]
xref: EC:3.-.-.-
xref: Reactome:REACT_100692 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Rattus norvegicus"
xref: Reactome:REACT_101782 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Danio rerio"
xref: Reactome:REACT_103715 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Canis familiaris"
xref: Reactome:REACT_113833 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Xenopus tropicalis"
xref: Reactome:REACT_1777 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Homo sapiens"
xref: Reactome:REACT_34799 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Sus scrofa"
xref: Reactome:REACT_90230 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Mus musculus"
xref: Reactome:REACT_92319 "uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide, Bos taurus"
is_a: GO:0016787 ! hydrolase activity
AmiGO
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