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Category:GO:0003918 ! DNA topoisomerase (ATP-hydrolyzing) activity
name: DNA topoisomerase (ATP-hydrolyzing) activity
namespace: molecular_function
def: "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]
subset: gosubset_prok
synonym: "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.3]
synonym: "deoxyribonucleic topoisomerase activity" EXACT [EC:5.99.1.3]
synonym: "DNA gyrase activity" EXACT []
synonym: "DNA topoisomerase (ATP-hydrolysing)" BROAD [EC:5.99.1.3]
synonym: "DNA topoisomerase II" RELATED [EC:5.99.1.3]
synonym: "DNA topoisomerase IV activity" EXACT []
synonym: "DNA topoisomerase type II activity" EXACT []
synonym: "DNA-gyrase activity" EXACT [EC:5.99.1.3]
synonym: "topoisomerase" BROAD [EC:5.99.1.3]
synonym: "topoisomerase II" EXACT []
synonym: "type II DNA topoisomerase activity" EXACT [EC:5.99.1.3]
xref: EC:5.99.1.3
xref: MetaCyc:5.99.1.3-RXN
xref: Wikipedia:Type_II_topoisomerase
is_a: GO:0003916 ! DNA topoisomerase activity
is_a: GO:0008094 ! DNA-dependent ATPase activity
AmiGO
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Pages in category "GO:0003918 ! DNA topoisomerase (ATP-hydrolyzing) activity"
The following 67 pages are in this category, out of 67 total.
