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Category:GO:0003917 ! DNA topoisomerase type I activity
name: DNA topoisomerase type I activity
namespace: molecular_function
def: "Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle." [PMID:8811192]
comment: Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
subset: gosubset_prok
synonym: "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.2]
synonym: "DNA topoisomerase I activity" NARROW []
synonym: "nicking-closing enzyme activity" RELATED [EC:5.99.1.2]
synonym: "omega-protein activity" RELATED [EC:5.99.1.2]
synonym: "relaxing enzyme activity" RELATED [EC:5.99.1.2]
synonym: "swivelase activity" RELATED [EC:5.99.1.2]
synonym: "topoisomerase" BROAD [EC:5.99.1.2]
synonym: "type I DNA topoisomerase activity" EXACT []
synonym: "type I topoisomerase activity" EXACT []
synonym: "untwisting enzyme activity" RELATED [EC:5.99.1.2]
xref: EC:5.99.1.2
xref: MetaCyc:5.99.1.2-RXN
is_a: GO:0003916 ! DNA topoisomerase activity
AmiGO
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Pages in category "GO:0003917 ! DNA topoisomerase type I activity"
The following 47 pages are in this category, out of 47 total.
