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Category:GO:0003909 ! DNA ligase activity
name: DNA ligase activity
namespace: molecular_function
def: "Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+." [ISBN:0716720094]
subset: gosubset_prok
xref: EC:6.5.1.-
xref: Reactome:REACT_100095 "DNA ligation via the single-nucleotide replacement pathway, Bos taurus"
xref: Reactome:REACT_100592 "Joining of adjacent Okazaki fragments, Canis familiaris"
xref: Reactome:REACT_101774 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Caenorhabditis elegans"
xref: Reactome:REACT_102755 "Ligation of DNA and formation of Holliday structures following repair synthesis, Gallus gallus"
xref: Reactome:REACT_102810 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Saccharomyces cerevisiae"
xref: Reactome:REACT_102989 "Ligation of DNA at sites of patch replacement, Rattus norvegicus"
xref: Reactome:REACT_103194 "Joining of adjacent Okazaki fragments, Mus musculus"
xref: Reactome:REACT_103238 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Canis familiaris"
xref: Reactome:REACT_103332 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Drosophila melanogaster"
xref: Reactome:REACT_103589 "Ligation of DNA and formation of Holliday structures following repair synthesis, Mycobacterium tuberculosis"
xref: Reactome:REACT_103607 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Mus musculus"
xref: Reactome:REACT_103914 "Ligation of DNA and formation of Holliday structures following repair synthesis, Plasmodium falciparum"
xref: Reactome:REACT_104033 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Sus scrofa"
xref: Reactome:REACT_105041 "Ligation of DNA and formation of Holliday structures following repair synthesis, Saccharomyces cerevisiae"
xref: Reactome:REACT_105804 "Ligation of DNA and formation of Holliday structures following repair synthesis, Dictyostelium discoideum"
xref: Reactome:REACT_106130 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Xenopus tropicalis"
xref: Reactome:REACT_106909 "Ligation of DNA and formation of Holliday structures following repair synthesis, Canis familiaris"
xref: Reactome:REACT_106919 "Joining of adjacent Okazaki fragments of the C-strand, Oryza sativa"
xref: Reactome:REACT_107577 "Ligation of DNA and formation of Holliday structures following repair synthesis, Drosophila melanogaster"
xref: Reactome:REACT_107734 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Mus musculus"
xref: Reactome:REACT_107864 "DNA ligation via the single-nucleotide replacement pathway, Dictyostelium discoideum"
xref: Reactome:REACT_108464 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Rattus norvegicus"
xref: Reactome:REACT_108675 "Ligation of DNA at sites of patch replacement, Mus musculus"
xref: Reactome:REACT_109229 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Plasmodium falciparum"
xref: Reactome:REACT_109434 "Joining of adjacent Okazaki fragments, Mycobacterium tuberculosis"
xref: Reactome:REACT_109730 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Schizosaccharomyces pombe"
xref: Reactome:REACT_109841 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Saccharomyces cerevisiae"
xref: Reactome:REACT_110352 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Caenorhabditis elegans"
xref: Reactome:REACT_112118 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Mus musculus"
xref: Reactome:REACT_112246 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Sus scrofa"
xref: Reactome:REACT_113076 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Xenopus tropicalis"
xref: Reactome:REACT_113217 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Gallus gallus"
xref: Reactome:REACT_113661 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Canis familiaris"
xref: Reactome:REACT_113851 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Bos taurus"
xref: Reactome:REACT_114038 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Rattus norvegicus"
xref: Reactome:REACT_114285 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Danio rerio"
xref: Reactome:REACT_114706 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Taeniopygia guttata"
xref: Reactome:REACT_115886 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Gallus gallus"
xref: Reactome:REACT_12 "Removal of repair proteins and ligation of the processed ends of the DNA double-strand break, Homo sapiens"
xref: Reactome:REACT_1247 "Ligation of DNA at sites of patch replacement, Homo sapiens"
xref: Reactome:REACT_1659 "DNA ligation via the single-nucleotide replacement pathway, Homo sapiens"
xref: Reactome:REACT_1889 "Joining of adjacent Okazaki fragments, Homo sapiens"
xref: Reactome:REACT_2181 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Homo sapiens"
xref: Reactome:REACT_29134 "Ligation of DNA and formation of Holliday structures following repair synthesis, Rattus norvegicus"
xref: Reactome:REACT_29359 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Oryza sativa"
xref: Reactome:REACT_29498 "Joining of adjacent Okazaki fragments of the C-strand, Mus musculus"
xref: Reactome:REACT_29665 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Bos taurus"
xref: Reactome:REACT_29882 "Ligation of DNA at sites of patch replacement, Xenopus tropicalis"
xref: Reactome:REACT_30614 "Joining of adjacent Okazaki fragments, Caenorhabditis elegans"
xref: Reactome:REACT_31624 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Arabidopsis thaliana"
xref: Reactome:REACT_31707 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Dictyostelium discoideum"
xref: Reactome:REACT_31800 "Ligation of DNA at sites of patch replacement, Sus scrofa"
xref: Reactome:REACT_32203 "Joining of adjacent Okazaki fragments, Gallus gallus"
xref: Reactome:REACT_32488 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Rattus norvegicus"
xref: Reactome:REACT_33776 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Gallus gallus"
xref: Reactome:REACT_34177 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Bos taurus"
xref: Reactome:REACT_34490 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Danio rerio"
xref: Reactome:REACT_527 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Homo sapiens"
xref: Reactome:REACT_77023 "Ligation of DNA and formation of Holliday structures following repair synthesis, Mus musculus"
xref: Reactome:REACT_77057 "Joining of adjacent Okazaki fragments, Dictyostelium discoideum"
xref: Reactome:REACT_78542 "Joining of adjacent Okazaki fragments, Sus scrofa"
xref: Reactome:REACT_78969 "Joining of adjacent Okazaki fragments of the C-strand, Bos taurus"
xref: Reactome:REACT_79227 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Sus scrofa"
xref: Reactome:REACT_79753 "Joining of adjacent Okazaki fragments, Xenopus tropicalis"
xref: Reactome:REACT_7994 "Joining of adjacent Okazaki fragments of the C-strand, Homo sapiens"
xref: Reactome:REACT_80840 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Xenopus tropicalis"
xref: Reactome:REACT_81358 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Dictyostelium discoideum"
xref: Reactome:REACT_81832 "Ligation of DNA and formation of Holliday structures following repair synthesis, Sus scrofa"
xref: Reactome:REACT_819 "Ligation of DNA and formation of Holliday structures following repair synthesis, Homo sapiens"
xref: Reactome:REACT_81990 "Joining of adjacent Okazaki fragments of the C-strand, Danio rerio"
xref: Reactome:REACT_82032 "Joining of adjacent Okazaki fragments, Schizosaccharomyces pombe"
xref: Reactome:REACT_82667 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Schizosaccharomyces pombe"
xref: Reactome:REACT_82701 "DNA ligation via the single-nucleotide replacement pathway, Xenopus tropicalis"
xref: Reactome:REACT_82930 "Ligation of DNA and formation of Holliday structures following repair synthesis, Caenorhabditis elegans"
xref: Reactome:REACT_83571 "Ligation of DNA at sites of patch replacement, Danio rerio"
xref: Reactome:REACT_84527 "Joining of adjacent Okazaki fragments of the C-strand, Xenopus tropicalis"
xref: Reactome:REACT_84993 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Arabidopsis thaliana"
xref: Reactome:REACT_85398 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Drosophila melanogaster"
xref: Reactome:REACT_85781 "Joining of adjacent Okazaki fragments of the C-strand, Schizosaccharomyces pombe"
xref: Reactome:REACT_85839 "Joining of adjacent Okazaki fragments, Plasmodium falciparum"
xref: Reactome:REACT_85910 "Joining of adjacent Okazaki fragments of the C-strand, Canis familiaris"
xref: Reactome:REACT_85997 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Canis familiaris"
xref: Reactome:REACT_86056 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Gallus gallus"
xref: Reactome:REACT_86721 "Joining of adjacent Okazaki fragments, Saccharomyces cerevisiae"
xref: Reactome:REACT_87237 "Ligation of DNA at sites of patch replacement, Arabidopsis thaliana"
xref: Reactome:REACT_88790 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Oryza sativa"
xref: Reactome:REACT_88893 "Joining of adjacent Okazaki fragments, Rattus norvegicus"
xref: Reactome:REACT_89311 "DNA ligation via the single-nucleotide replacement pathway, Mus musculus"
xref: Reactome:REACT_89618 "Joining of adjacent Okazaki fragments of the C-strand, Rattus norvegicus"
xref: Reactome:REACT_89621 "Ligation of DNA and formation of Holliday structures following repair synthesis, Bos taurus"
xref: Reactome:REACT_89952 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Plasmodium falciparum"
xref: Reactome:REACT_90164 "Joining of adjacent Okazaki fragments, Drosophila melanogaster"
xref: Reactome:REACT_90240 "Ligation of DNA and formation of Holliday structures following repair synthesis, Oryza sativa"
xref: Reactome:REACT_90705 "Joining of adjacent Okazaki fragments, Danio rerio"
xref: Reactome:REACT_9073 "2-LTR formation due to circularization of viral DNA, Homo sapiens"
xref: Reactome:REACT_90997 "Joining of adjacent Okazaki fragments, Oryza sativa"
xref: Reactome:REACT_91447 "Ligation of DNA at sites of patch replacement, Canis familiaris"
xref: Reactome:REACT_91602 "DNA ligation via the single-nucleotide replacement pathway, Canis familiaris"
xref: Reactome:REACT_92092 "Joining of adjacent Okazaki fragments of the C-strand, Sus scrofa"
xref: Reactome:REACT_92345 "Joining of adjacent Okazaki fragments, Arabidopsis thaliana"
xref: Reactome:REACT_92550 "Ligation of DNA and formation of Holliday structures following repair synthesis, Arabidopsis thaliana"
xref: Reactome:REACT_92807 "Ligation of DNA at sites of patch replacement, Bos taurus"
xref: Reactome:REACT_93826 "DNA ligation via the single-nucleotide replacement pathway, Danio rerio"
xref: Reactome:REACT_94103 "DNA ligation via the single-nucleotide replacement pathway, Rattus norvegicus"
xref: Reactome:REACT_94317 "Joining of adjacent Okazaki fragments of the C-strand, Arabidopsis thaliana"
xref: Reactome:REACT_95309 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Mycobacterium tuberculosis"
xref: Reactome:REACT_95407 "Ligation of newly synthesized repair patch to incised DNA in GG-NER, Mycobacterium tuberculosis"
xref: Reactome:REACT_96323 "Ligation of DNA and formation of Holliday structures following repair synthesis, Schizosaccharomyces pombe"
xref: Reactome:REACT_97779 "Ligation of DNA and formation of Holliday structures following repair synthesis, Xenopus tropicalis"
xref: Reactome:REACT_97800 "Ligation of DNA and formation of Holliday structures following repair synthesis, Danio rerio"
xref: Reactome:REACT_98012 "Joining of adjacent Okazaki fragments, Bos taurus"
xref: Reactome:REACT_98339 "Ligation of DNA at sites of patch replacement, Oryza sativa"
xref: Reactome:REACT_99685 "Ligation of newly synthesized repair patch to incised DNA in TC-NER, Danio rerio"
is_a: GO:0016886 ! ligase activity, forming phosphoric ester bonds
AmiGO
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