Category:GO:0002753 ! cytoplasmic pattern recognition receptor signaling pathway

name: cytoplasmic pattern recognition receptor signaling pathway
namespace: biological_process
alt_id: GO:0039528
def: "The series of molecular signals initiated by the binding of a ligand from another organism to a cytoplasmic pattern recognition receptor (PRR). PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species." [GOC:add, GOC:ar, ISBN:0781735149, PMID:15199967, PMID:17328678, PMID:18272355, PMID:19531363, PMID:21187438]
comment: This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has been activated. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.
synonym: "cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway" NARROW [PMID:17328678]
synonym: "cytoplasmic pathogen receptor signaling pathway" EXACT []
synonym: "cytoplasmic pattern recognition receptor signalling pathway" EXACT []
synonym: "cytoplasmic PRR signaling pathway" EXACT []
synonym: "cytosolic PAMP receptor signaling pathway" EXACT []
synonym: "cytosolic pattern recognition receptor signaling pathway" EXACT []
is_a: GO:0002221 ! pattern recognition receptor signaling pathway
is_a: GO:0030522 ! intracellular receptor signaling pathway
relationship: has_part: GO:0001819 ! positive regulation of cytokine production

AmiGO <GOterm>GO:0002753</GOterm>
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