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Category:GO:0001301 ! progressive alteration of chromatin during cell aging
name: progressive alteration of chromatin during cell aging
namespace: biological_process
def: "The process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype." [GOC:jh, PMID:12044938]
synonym: "age-dependent accumulation of genetic damage" RELATED []
synonym: "progressive alteration of chromatin during cell ageing" EXACT []
is_a: GO:0016568 ! chromatin modification
relationship:part_of: GO:0007569 ! cell aging
AmiGO
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