Category:GO:0000398 ! nuclear mRNA splicing, via spliceosome

name: nuclear mRNA splicing, via spliceosome
namespace: biological_process
alt_id:GO:0006374
alt_id:GO:0006375
def: "The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." [GOC:krc, ISBN:0198506732, ISBN:0879695897]
comment: Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.
synonym: "mRNA splicing" BROAD []
synonym: "nuclear mRNA splicing via U12-type spliceosome" NARROW []
synonym: "nuclear mRNA splicing via U2-type spliceosome" NARROW []
synonym: "pre-mRNA splicing" BROAD []
synonym: "splicing AT-AC intron" RELATED []
synonym: "splicing GT-AG intron" RELATED []
xref: Reactome:REACT_101135 "mRNA Splicing - Minor Pathway, Drosophila melanogaster"
xref: Reactome:REACT_101749 "mRNA Splicing - Minor Pathway, Caenorhabditis elegans"
xref: Reactome:REACT_106268 "mRNA Splicing - Major Pathway, Gallus gallus"
xref: Reactome:REACT_107907 "mRNA Splicing - Minor Pathway, Schizosaccharomyces pombe"
xref: Reactome:REACT_109091 "mRNA Splicing - Minor Pathway, Rattus norvegicus"
xref: Reactome:REACT_112200 "mRNA Splicing - Major Pathway, Arabidopsis thaliana"
xref: Reactome:REACT_114266 "mRNA Splicing - Major Pathway, Oryza sativa"
xref: Reactome:REACT_114738 "mRNA Splicing - Major Pathway, Taeniopygia guttata"
xref: Reactome:REACT_1753 "mRNA Splicing - Minor Pathway, Homo sapiens"
xref: Reactome:REACT_30984 "mRNA Splicing - Minor Pathway, Plasmodium falciparum"
xref: Reactome:REACT_32449 "mRNA Splicing - Minor Pathway, Canis familiaris"
xref: Reactome:REACT_34020 "mRNA Splicing - Minor Pathway, Dictyostelium discoideum"
xref: Reactome:REACT_467 "mRNA Splicing - Major Pathway, Homo sapiens"
xref: Reactome:REACT_81417 "mRNA Splicing - Major Pathway, Canis familiaris"
xref: Reactome:REACT_82149 "mRNA Splicing - Minor Pathway, Danio rerio"
xref: Reactome:REACT_85452 "mRNA Splicing - Major Pathway, Bos taurus"
xref: Reactome:REACT_86489 "mRNA Splicing - Minor Pathway, Mus musculus"
xref: Reactome:REACT_88186 "mRNA Splicing - Minor Pathway, Oryza sativa"
xref: Reactome:REACT_89168 "mRNA Splicing - Minor Pathway, Gallus gallus"
xref: Reactome:REACT_90296 "mRNA Splicing - Major Pathway, Danio rerio"
xref: Reactome:REACT_91088 "mRNA Splicing - Minor Pathway, Arabidopsis thaliana"
xref: Reactome:REACT_91611 "mRNA Splicing - Major Pathway, Drosophila melanogaster"
xref: Reactome:REACT_91773 "mRNA Splicing - Minor Pathway, Bos taurus"
xref: Reactome:REACT_93740 "mRNA Splicing - Major Pathway, Caenorhabditis elegans"
xref: Reactome:REACT_93843 "mRNA Splicing - Major Pathway, Rattus norvegicus"
xref: Reactome:REACT_95764 "mRNA Splicing - Major Pathway, Mus musculus"
xref: Reactome:REACT_99123 "mRNA Splicing - Major Pathway, Xenopus tropicalis"
xref: Reactome:REACT_99763 "mRNA Splicing - Minor Pathway, Xenopus tropicalis"
is_a: GO:0000377 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
is_a: GO:0006397 ! mRNA processing

AmiGO

Child Terms

This term has the following 11 child terms, out of 11 total.

Pages in category "GO:0000398 ! nuclear mRNA splicing, via spliceosome"

The following 200 pages are in this category, out of 523 total.