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CLODI:TOXB
Contents |
| Species (Taxon ID) | Clostridium difficile. (taxon:1496) | |
| Gene Name(s) | toxB ( synonyms: tcdB ) | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | TOXB_CLODI | |
| UniProt Accessions | P18177, | |
| EMBL | X53138, X92982, X60984, | |
| PIR | A27636, S10317, | |
| PDB | 2BVL, 2BVM, | |
| Pfam | PF01473, PF11713, | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0046527 |
glucosyltransferase activity |
IDA: Inferred from Direct Assay |
|
F |
||||
| GO:0009405 |
pathogenesis |
IEA: Inferred from Electronic Annotation |
P |
|||||
| GO:0046527 |
glucosyltransferase activity |
IDA: Inferred from Direct Assay |
F |
|||||
| GO:0009405 |
pathogenesis |
IMP: Inferred from Mutant Phenotype |
P |
Figure 2ab utilizes toxin end point titre and cytotoxic effects on Vero and HT29 cells, while figure 2cd measures toxin neutralization assays. Figure 3a measures the time between innoculation and colonization in the hamster specimins between the different mutants. Figure 3b measures the time from colonization to death of the specimins between the different mutant strains. |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Wu ZL et al. (2011) Universal phosphatase-coupled glycosyltransferase assay. Glycobiology 21: 727-33 PubMed GONUTS page
- ↑ Kuehne SA et al. (2010) The role of toxin A and toxin B in Clostridium difficile infection. Nature 467: 711-3 PubMed GONUTS page
