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CHLAE:CATL1
Contents |
| Species (Taxon ID) | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops). ([1]) | |
| Gene Name(s) | CTSL1 (synonyms: CTSL) | |
| Protein Name(s) | Cathepsin L1
Major excreted protein MEP Cathepsin L1 heavy chain Cathepsin L1 light chain | |
| External Links | ||
| EMBL | AF201700 | |
| HSSP | P07711 | |
| ProteinModelPortal | Q9GKL8 | |
| SMR | Q9GKL8 | |
| MEROPS | C01.032 I29.001 | |
| HOVERGEN | HBG011513 | |
| GO | GO:0005764 GO:0004197 GO:0006508 | |
| InterPro | IPR000169 IPR013128 IPR000668 IPR013201 | |
| PANTHER | PTHR12411 | |
| Pfam | PF08246 PF00112 | |
| PRINTS | PR00705 | |
| SMART | SM00848 SM00645 | |
| PROSITE | PS00640 PS00139 PS00639 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004197 |
cysteine-type endopeptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005764 |
lysosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005764 |
lysosome |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0158 |
C |
Seeded From UniProt |
|||
| GO:0006508 |
proteolysis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006508 |
proteolysis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008233 |
peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008234 |
cysteine-type peptidase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0019059 |
initiation of viral infection |
IMP: Inferred from Mutant Phenotype |
P |
Fig. 1B and Fig. 2D CatL is not required for infection, but does enhance infection when CatB is activated. |
complete | |||
| GO:0016787 |
hydrolase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004197 |
cysteine-type endopeptidase activity |
IMP: Inferred from Mutant Phenotype |
F |
Fig. 1B and Fig. 2B |
complete | |||
| GO:0019059 |
initiation of viral infection |
IDA: Inferred from Direct Assay |
P |
Fig. 1A, 1C and Fig. 3(A,B,C) |
complete | |||
| GO:0004197 |
cysteine-type endopeptidase activity |
IDA: Inferred from Direct Assay |
F |
Fig. 2 |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Chandran K et al. (2005) Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308: 1643-5 PubMed GONUTS page
- ↑ 2.0 2.1 Schornberg K et al. (2006) Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J Virol 80: 4174-8 PubMed GONUTS page
