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CHICK:SRC

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) SRC
Protein Name(s) Proto-oncogene tyrosine-protein kinase Src

Proto-oncogene c-Src pp60c-src p60-Src

External Links
UniProt P00523
EMBL V00402
J00908
M57290
S43604
S43616
S43587
S43609
S43614
S43579
PIR A00630
RefSeq NP_990788.2
UniGene Gga.46254
Gga.51508
Gga.9406
PDB 1F1W
1F2F
1NLO
1NLP
1P13
1PRL
1PRM
1RLP
1RLQ
1SRL
1SRM
2HWO
2HWP
2OIQ
2PTK
2QI8
2QLQ
2QQ7
3D7T
3D7U
3DQW
3DQX
3EL7
3EL8
3EN4
3EN5
3EN6
3EN7
3F3T
3F3U
3F3V
3F3W
3F6X
3FJ5
3G5D
3G6G
3G6H
3GEQ
3LOK
3OEZ
3OF0
3QLF
3QLG
3SVV
3TZ7
3TZ8
3TZ9
3U4W
3U51
3UQF
3UQG
4AGW
4DGG
4FIC
4HVU
4HVV
4HVW
4JZ3
4JZ4
4LE9
4LGG
4LGH
4MCV
4U5J
PDBsum 1F1W
1F2F
1NLO
1NLP
1P13
1PRL
1PRM
1RLP
1RLQ
1SRL
1SRM
2HWO
2HWP
2OIQ
2PTK
2QI8
2QLQ
2QQ7
3D7T
3D7U
3DQW
3DQX
3EL7
3EL8
3EN4
3EN5
3EN6
3EN7
3F3T
3F3U
3F3V
3F3W
3F6X
3FJ5
3G5D
3G6G
3G6H
3GEQ
3LOK
3OEZ
3OF0
3QLF
3QLG
3SVV
3TZ7
3TZ8
3TZ9
3U4W
3U51
3UQF
3UQG
4AGW
4DGG
4FIC
4HVU
4HVV
4HVW
4JZ3
4JZ4
4LE9
4LGG
4LGH
4MCV
4U5J
ProteinModelPortal P00523
SMR P00523
BioGrid 676691
DIP DIP-449N
IntAct P00523
MINT MINT-139173
BindingDB P00523
ChEMBL CHEMBL3655
PaxDb P00523
Ensembl ENSGALT00000006127
GeneID 396442
KEGG gga:396442
CTD 6714
eggNOG COG0515
GeneTree ENSGT00760000118938
HOVERGEN HBG008761
InParanoid P00523
KO K05704
OMA CHRLTNV
OrthoDB EOG7GTT2V
PhylomeDB P00523
TreeFam TF351634
BRENDA 2.7.10.2
Reactome REACT_189763
REACT_194391
REACT_196766
REACT_204997
REACT_207020
REACT_217737
REACT_220416
REACT_226416
REACT_230783
REACT_235751
REACT_239556
REACT_240004
REACT_240643
REACT_241087
REACT_246174
REACT_246236
REACT_246525
REACT_248632
REACT_250039
REACT_250385
REACT_252845
REACT_253490
REACT_253932
REACT_254941
REACT_257494
REACT_257604
REACT_262164
EvolutionaryTrace P00523
NextBio 20816483
PRO PR:P00523
Proteomes UP000000539
ExpressionAtlas P00523
GO GO:0005901
GO:0005856
GO:0005829
GO:0010008
GO:0070062
GO:0005770
GO:0005764
GO:0005743
GO:0005634
GO:0005524
GO:0020037
GO:0004715
GO:0019903
GO:0007155
GO:0007049
GO:0016477
GO:0030900
GO:0002376
GO:0035556
GO:2000811
GO:0043154
GO:2001237
GO:2001243
GO:0051902
GO:0032463
GO:0048477
GO:0090263
GO:0071803
GO:0051897
GO:0046777
GO:0033146
GO:0043393
GO:0070555
GO:0060065
Gene3D 3.30.505.10
InterPro IPR011009
IPR000719
IPR017441
IPR001245
IPR000980
IPR001452
IPR008266
IPR020635
Pfam PF07714
PF00017
PF00018
PRINTS PR00401
PR00452
PR00109
SMART SM00252
SM00326
SM00219
SUPFAM SSF50044
SSF55550
SSF56112
PROSITE PS00107
PS50011
PS00109
PS50001
PS50002

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

F

complete

GO:0004672

protein kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

complete

GO:0004672

protein kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

F

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0829

F

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.10.2

F

complete

GO:0005102

receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0005515

protein binding

PMID:11279199[1]

IPI: Inferred from Physical Interaction

UniProtKB:P63244

F

complete

GO:0005515

protein binding

PMID:17525734[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWI6-2

F

complete

GO:0005515

protein binding

PMID:18614016[3]

IPI: Inferred from Physical Interaction

UniProtKB:P41240

F

complete

GO:0005515

protein binding

PMID:9819391[4]

IPI: Inferred from Physical Interaction

UniProtKB:O97902

F

complete

GO:0005515

protein binding

PMID:9819391[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWY8-1

F

complete

GO:0005515

protein binding

PMID:9819391[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWY8-2

F

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

complete

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

C

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P12003

C

complete

GO:0005829

cytosol

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

C

complete

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

complete

GO:0005886

plasma membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

C

complete

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

complete

GO:0005901

caveola

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

C

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0007243

intracellular protein kinase cascade

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

P

complete

GO:0007265

Ras protein signal transduction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

P

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

complete

GO:0016044

cellular membrane organization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

P

complete

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

complete

GO:0016301

kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

complete

GO:0016301

kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

complete

GO:0016310

phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0016310

phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

P

complete

GO:0016477

cell migration

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

complete

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

complete

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0019904

protein domain specific binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

complete

GO:0020037

heme binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0020037

heme binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P12931

F

complete

GO:0030900

forebrain development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0033146

regulation of estrogen receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0042169

SH2 domain binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0044325

ion channel binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

F

complete

GO:0048477

oogenesis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0060065

uterus development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0060444

branching involved in mammary gland duct morphogenesis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

complete

GO:0070555

response to interleukin-1

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000408503

P

complete

GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0002376

immune system process

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0391

P

Seeded From UniProt

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

Seeded From UniProt

complete

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.10.2

F

Seeded From UniProt

complete

GO:0004715

non-membrane spanning protein tyrosine kinase activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

F

Seeded From UniProt

complete

GO:0005102

receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:10512882[5]

IPI: Inferred from Physical Interaction

UniProtKB:Q00944

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:10698938[6]

IPI: Inferred from Physical Interaction

UniProtKB:P18433

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:11279199[1]

IPI: Inferred from Physical Interaction

UniProtKB:P63244

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:11923305[7]

IPI: Inferred from Physical Interaction

UniProtKB:P18433

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:12834342[8]

IPI: Inferred from Physical Interaction

UniProtKB:P18052

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:16079136[9]

IPI: Inferred from Physical Interaction

UniProtKB:O88703

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:16630611[10]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Y4D1

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:16831863[11]

IPI: Inferred from Physical Interaction

UniProtKB:Q9NZA1

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:17525734[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWI6-2

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:18614016[3]

IPI: Inferred from Physical Interaction

UniProtKB:P41240

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:21236256[12]

IPI: Inferred from Physical Interaction

UniProtKB:Q90738

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:9425168[13]

IPI: Inferred from Physical Interaction

UniProtKB:Q00944

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:9655255[14]

IPI: Inferred from Physical Interaction

UniProtKB:Q90738

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:9819391[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWY8-1

F

Seeded From UniProt

complete

GO:0005515

protein binding

PMID:9819391[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QWY8-2

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

C

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P12003

C

Seeded From UniProt

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0999

C

Seeded From UniProt

complete

GO:0005743

mitochondrial inner membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0168

C

Seeded From UniProt

complete

GO:0005764

lysosome

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005768

endosome

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

GO:0005770

late endosome

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005829

cytosol

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005829

cytosol

Reactome:REACT_264525

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005829

cytosol

Reactome:REACT_264550

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005829

cytosol

Reactome:REACT_264561

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005856

cytoskeleton

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

GO:0005856

cytoskeleton

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

GO:0005884

actin filament

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0005901

caveola

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266
InterPro:IPR020635

P

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0007049

cell cycle

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

GO:0007155

cell adhesion

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0007155

cell adhesion

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

GO:0007173

epidermal growth factor receptor signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0007179

transforming growth factor beta receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0007229

integrin-mediated signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0010008

endosome membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0100

C

Seeded From UniProt

complete

GO:0010632

regulation of epithelial cell migration

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016301

kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

Seeded From UniProt

complete

GO:0016301

kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

GO:0016310

phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0016310

phosphorylation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

GO:0016477

cell migration

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0019899

enzyme binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0019903

protein phosphatase binding

PMID:15696169[15]

IPI: Inferred from Physical Interaction

UniProtKB:P17706-2

F

Seeded From UniProt

complete

GO:0019904

protein domain specific binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

F

Seeded From UniProt

complete

GO:0020037

heme binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0020037

heme binding

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P12931

F

Seeded From UniProt

complete

GO:0022407

regulation of cell-cell adhesion

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0030154

cell differentiation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0030900

forebrain development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0031234

extrinsic component of cytoplasmic side of plasma membrane

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

C

Seeded From UniProt

complete

GO:0031648

protein destabilization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0032463

negative regulation of protein homooligomerization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0032587

ruffle membrane

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

C

Seeded From UniProt

complete

GO:0033146

regulation of intracellular estrogen receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0034446

substrate adhesion-dependent cell spreading

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0034614

cellular response to reactive oxygen species

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0035556

intracellular signal transduction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0036035

osteoclast development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0036035

osteoclast development

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0036120

cellular response to platelet-derived growth factor stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0038083

peptidyl-tyrosine autophosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0042127

regulation of cell proliferation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0042169

SH2 domain binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0043066

negative regulation of apoptotic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0043149

stress fiber assembly

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0043393

regulation of protein binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0044325

ion channel binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0045087

innate immune response

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000700357

P

Seeded From UniProt

complete

GO:0045453

bone resorption

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0045453

bone resorption

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0046777

protein autophosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0046875

ephrin receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

C

Seeded From UniProt

complete

GO:0048477

oogenesis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0050847

progesterone receptor signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0051219

phosphoprotein binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0051427

hormone receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

F

Seeded From UniProt

complete

GO:0051726

regulation of cell cycle

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0051897

positive regulation of protein kinase B signaling

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0051902

negative regulation of mitochondrial depolarization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0060065

uterus development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0060491

regulation of cell projection assembly

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0070062

extracellular exosome

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

C

Seeded From UniProt

complete

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0070555

response to interleukin-1

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:0070851

growth factor receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:0070851

growth factor receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

F

Seeded From UniProt

complete

GO:0071375

cellular response to peptide hormone stimulus

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN001231381

P

Seeded From UniProt

complete

GO:0071498

cellular response to fluid shear stress

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0071560

cellular response to transforming growth factor beta stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0071801

regulation of podosome assembly

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:0071803

positive regulation of podosome assembly

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0086098

angiotensin-activated signaling pathway involved in heart process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0090263

positive regulation of canonical Wnt signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000090237

P

Seeded From UniProt

complete

GO:0097110

scaffold protein binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

F

Seeded From UniProt

complete

GO:2000641

regulation of early endosome to late endosome transport

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:2000811

negative regulation of anoikis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:2001237

negative regulation of extrinsic apoptotic signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:2001237

negative regulation of extrinsic apoptotic signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:2001243

negative regulation of intrinsic apoptotic signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

GO:2001243

negative regulation of intrinsic apoptotic signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000701141

P

Seeded From UniProt

complete

GO:2001286

regulation of caveolin-mediated endocytosis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000362680

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Chang, BY et al. (2001) The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1. J. Biol. Chem. 276 20346-56 PubMed GONUTS page
  2. 2.0 2.1 Di Stefano, P et al. (2007) p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity. EMBO J. 26 2843-55 PubMed GONUTS page
  3. 3.0 3.1 Levinson, NM et al. (2008) Structural basis for the recognition of c-Src by its inactivator Csk. Cell 134 124-34 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Brown, MT et al. (1998) ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src. Mol. Cell. Biol. 18 7038-51 PubMed GONUTS page
  5. Schaller, MD et al. (1999) Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases. Mol. Biol. Cell 10 3489-505 PubMed GONUTS page
  6. Zheng, XM et al. (2000) A phosphotyrosine displacement mechanism for activation of Src by PTPalpha. EMBO J. 19 964-78 PubMed GONUTS page
  7. Zheng, XM et al. (2002) Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation. J. Biol. Chem. 277 21922-9 PubMed GONUTS page
  8. Sonnenburg, ED et al. (2003) The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region. Biochemistry 42 7904-14 PubMed GONUTS page
  9. Zong, X et al. (2005) A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase. J. Biol. Chem. 280 34224-32 PubMed GONUTS page
  10. Aspenström, P et al. (2006) The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. Exp. Cell Res. 312 2180-94 PubMed GONUTS page
  11. Edwards, JC et al. (2006) c-Src control of chloride channel support for osteoclast HCl transport and bone resorption. J. Biol. Chem. 281 28011-22 PubMed GONUTS page
  12. Han, B et al. (2011) Actin filament associated protein mediates c-Src related SRE/AP-1 transcriptional activation. FEBS Lett. 585 471-7 PubMed GONUTS page
  13. Cary, LA et al. (1998) Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. J. Cell Biol. 140 211-21 PubMed GONUTS page
  14. Guappone, AC et al. (1998) Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif. Mol. Carcinog. 22 110-9 PubMed GONUTS page
  15. van Vliet, C et al. (2005) Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase. Nat. Immunol. 6 253-60 PubMed GONUTS page