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CHICK:Q9PUI3

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) WNT2B
Protein Name(s) Protein Wnt-2b
External Links
UniProt Q98SN7
EMBL AF346628
AF182403
RefSeq NP_989667.1
UniGene Gga.50310
IntAct Q98SN7
STRING 9031.ENSGALP00000039420
PaxDb Q98SN7
PRIDE Q98SN7
GeneID 374243
KEGG gga:374243
CTD 7482
eggNOG NOG284879
HOGENOM HOG000039529
HOVERGEN HBG001595
InParanoid Q98SN7
KO K00182
PhylomeDB Q98SN7
NextBio 20813739
PRO PR:Q98SN7
Proteomes UP000000539
GO GO:0005578
GO:0005109
GO:0060219
GO:0060070
GO:0008283
GO:0061303
GO:0060900
GO:0035115
GO:0061072
GO:0002088
GO:0002011
GO:0045686
GO:0045665
GO:0003407
GO:0030182
GO:0045743
GO:0060828
GO:0010842
GO:0016055
InterPro IPR005817
IPR009140
IPR018161
PANTHER PTHR12027
Pfam PF00110
PRINTS PR01842
PR01349
SMART SM00097
PROSITE PS00246

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002011

morphogenesis of an epithelial sheet

PMID:12921742[1]

IDA: Inferred from Direct Assay

P

complete

GO:0002088

lens development in camera-type eye

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

complete

GO:0003407

neural retina development

PMID:15901663[3]

TAS: Traceable Author Statement

P

complete

GO:0004871

signal transducer activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009140

F

complete

GO:0005109

frizzled binding

PMID:12490564[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q13467

F

complete

GO:0005109

frizzled binding

PMID:12490564[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q61088

F

complete

GO:0005575

cellular component

GO_REF:0000015

ND: No biological Data available

C

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005816

C

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

C

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009140

C

complete

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

complete

GO:0005578

proteinaceous extracellular matrix

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0272

C

complete

GO:0005578

proteinaceous extracellular matrix

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0111

C

complete

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005816

P

complete

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

P

complete

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009140

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005816

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009140

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

complete

GO:0008283

cell proliferation

PMID:10398532[5]

IEP: Inferred from Expression Pattern

P

complete

GO:0008283

cell proliferation

PMID:12490564[4]

IDA: Inferred from Direct Assay

P

complete

GO:0008283

cell proliferation

PMID:15901663[3]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0010842

retina layer formation

PMID:12921742[1]

IDA: Inferred from Direct Assay

P

complete

GO:0016055

Wnt receptor signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0879

P

complete

GO:0016055

Wnt receptor signaling pathway

PMID:12921742[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0030182

neuron differentiation

PMID:16854977[6]

IEP: Inferred from Expression Pattern

P

complete

GO:0035115

embryonic forelimb morphogenesis

PMID:11290326[7]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0045665

negative regulation of neuron differentiation

PMID:12490564[4]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0045665

negative regulation of neuron differentiation

PMID:12921742[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0045665

negative regulation of neuron differentiation

PMID:15901663[3]

IDA: Inferred from Direct Assay

P

complete

GO:0045686

negative regulation of glial cell differentiation

PMID:15901663[3]

IDA: Inferred from Direct Assay

P

complete

GO:0045743

positive regulation of fibroblast growth factor receptor signaling pathway

PMID:11290326[7]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0060070

canonical Wnt receptor signaling pathway

PMID:12490564[4]

IDA: Inferred from Direct Assay

P

complete

GO:0060070

canonical Wnt receptor signaling pathway

PMID:16854977[6]

IDA: Inferred from Direct Assay

P

complete

GO:0060219

camera-type eye photoreceptor cell differentiation

PMID:16854977[6]

IEP: Inferred from Expression Pattern

P

complete

GO:0060828

regulation of canonical Wnt receptor signaling pathway

PMID:11290326[7]

IDA: Inferred from Direct Assay

P

complete

GO:0060900

embryonic camera-type eye formation

PMID:12921742[1]

IEP: Inferred from Expression Pattern

P

complete

GO:0061072

iris morphogenesis

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

complete

GO:0002011

morphogenesis of an epithelial sheet

PMID:12921742[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0061303

cornea development in camera-type eye

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

complete

GO:0002088

lens development in camera-type eye

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0003407

neural retina development

PMID:15901663[3]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0005102

receptor binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009140

F

Seeded From UniProt

complete

GO:0005109

frizzled binding

PMID:12490564[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q13467

F

Seeded From UniProt

complete

GO:0005109

frizzled binding

PMID:12490564[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q61088

F

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009140

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005578

proteinaceous extracellular matrix

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0272

C

Seeded From UniProt

complete

GO:0005578

proteinaceous extracellular matrix

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0111

C

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009140

P

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

GO:0008283

cell proliferation

PMID:10398532[5]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0008283

cell proliferation

PMID:12490564[4]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0008283

cell proliferation

PMID:15901663[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0010842

retina layer formation

PMID:12921742[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005817
InterPro:IPR009140

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

PMID:12921742[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030182

neuron differentiation

PMID:16854977[6]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0035115

embryonic forelimb morphogenesis

PMID:11290326[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045665

negative regulation of neuron differentiation

PMID:12490564[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045665

negative regulation of neuron differentiation

PMID:12921742[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045665

negative regulation of neuron differentiation

PMID:15901663[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0045686

negative regulation of glial cell differentiation

PMID:15901663[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0045743

positive regulation of fibroblast growth factor receptor signaling pathway

PMID:11290326[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060070

canonical Wnt signaling pathway

PMID:12490564[4]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0060070

canonical Wnt signaling pathway

PMID:16854977[6]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0060173

limb development

PMID:16575901[8]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0060219

camera-type eye photoreceptor cell differentiation

PMID:16854977[6]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0060828

regulation of canonical Wnt signaling pathway

PMID:11290326[7]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0060900

embryonic camera-type eye formation

PMID:12921742[1]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0061072

iris morphogenesis

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0061303

cornea development in camera-type eye

PMID:16258938[2]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0090270

regulation of fibroblast growth factor production

PMID:11290326[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0090271

positive regulation of fibroblast growth factor production

PMID:16575901[8]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Nakagawa, S et al. (2003) Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Dev. Biol. 260 414-25 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Kubo, F et al. (2005) Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes. Development 132 2759-70 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 Kubo, F et al. (2003) Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130 587-98 PubMed GONUTS page
  5. 5.0 5.1 Jasoni, C et al. (1999) Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Dev. Dyn. 215 215-24 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 6.5 Cho, SH & Cepko, CL (2006) Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133 3167-77 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 7.4 7.5 7.6 Kawakami, Y et al. (2001) WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 104 891-900 PubMed GONUTS page
  8. 8.0 8.1 Dong, YF et al. (2006) Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J. Cell. Physiol. 208 77-86 PubMed GONUTS page