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CHICK:FGF1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) FGF1
Protein Name(s) Fibroblast growth factor 1

FGF-1 Acidic fibroblast growth factor aFGF Endothelial cell growth factor ECGF Heparin-binding growth factor 1 HBGF-1 Endothelial cell growth factor alpha

External Links
UniProt P19596
EMBL S63263
S63261
U31863
PIR A60130
RefSeq NP_990511.1
UniGene Gga.648
ProteinModelPortal P19596
SMR P19596
STRING 9031.ENSGALP00000011866
Ensembl ENSGALT00000011880
GeneID 396094
KEGG gga:396094
CTD 2246
eggNOG NOG246422
GeneTree ENSGT00730000110923
HOGENOM HOG000236341
HOVERGEN HBG007580
InParanoid P19596
KO K18496
OMA LGPRTHY
OrthoDB EOG7992S1
PhylomeDB P19596
TreeFam TF317805
Reactome REACT_284939
REACT_290454
REACT_301570
REACT_310443
REACT_322908
REACT_333432
REACT_338659
REACT_344129
REACT_347570
REACT_357371
REACT_357752
REACT_357807
REACT_358139
REACT_358141
REACT_358606
REACT_359074
REACT_359115
REACT_359511
REACT_360043
REACT_360791
REACT_361093
REACT_361101
REACT_361309
REACT_361442
REACT_361837
REACT_361899
REACT_362200
REACT_362215
REACT_362397
NextBio 20816152
PRO PR:P19596
Proteomes UP000000539
GO GO:0005938
GO:0005829
GO:0005576
GO:0005615
GO:0005654
GO:0005578
GO:0005104
GO:0008083
GO:0008201
GO:0044548
GO:0001525
GO:0060681
GO:0034605
GO:0003347
GO:0008543
GO:0030324
GO:0072163
GO:0001759
GO:0045766
GO:0051781
GO:0030335
GO:0008284
GO:0045542
GO:0050679
GO:1902533
GO:0043406
GO:0045944
GO:2000544
InterPro IPR008996
IPR028210
IPR002209
IPR028142
PANTHER PTHR11486
PTHR11486:SF65
PRINTS PR00263
PR00262
SMART SM00442
SUPFAM SSF50353
PROSITE PS00247

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0005178

integrin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

F

Seeded From UniProt

complete

involved_in

GO:1902533

positive regulation of intracellular signal transduction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0072163

mesonephric epithelium development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0060681

branch elongation involved in ureteric bud branching

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0051781

positive regulation of cell division

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0045766

positive regulation of angiogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0045542

positive regulation of cholesterol biosynthetic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

enables

GO:0044548

S100 protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

F

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

F

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

C

Seeded From UniProt

complete

enables

GO:0005104

fibroblast growth factor receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P05230

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0005104

fibroblast growth factor receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028210

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028210

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002209

F

Seeded From UniProt

complete

involved_in

GO:0008543

fibroblast growth factor receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028210

P

Seeded From UniProt

complete

involved_in

GO:0003347

epicardial cell to mesenchymal cell transition

PMID:20299672[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001525

angiogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0037

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0358

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

involved_in

GO:0051781

positive regulation of cell division

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0497

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0091

C

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0138

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Olivey, HE & Svensson, EC (2010) Epicardial-myocardial signaling directing coronary vasculogenesis. Circ. Res. 106 818-32 PubMed GONUTS page