CHICK:F1P4H2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	BMP6 (ECO:0000313 with Ensembl:ENSGALP00000020833)
Protein Name(s)	Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000020833)
External Links
UniProt	F1P4H2
EMBL	AADN03002635
ProteinModelPortal	F1P4H2
Ensembl	ENSGALT00000020862
GeneTree	ENSGT00760000118883
InParanoid	F1P4H2
OMA	DDENQPF
OrthoDB	EOG7J9VPQ
TreeFam	TF316134
Proteomes	UP000000539
GO	GO:0005576 GO:0030509 GO:0001958 GO:0001654 GO:0040007 GO:0006955 GO:0006954 GO:0001822 GO:0030539 GO:0001649 GO:0032349 GO:0030501 GO:0045603 GO:0001938 GO:0045666 GO:0045669 GO:0010862 GO:0060395 GO:0003323
Gene3D	2.10.90.10
InterPro	IPR029034 IPR001839 IPR001111 IPR015615 IPR017948
PANTHER	PTHR11848
Pfam	PF00019 PF00688
SMART	SM00204
SUPFAM	SSF57501
PROSITE	PS00250 PS51362

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0070700	BMP receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000932177 UniProtKB:P22003 UniProtKB:P22004	F	Seeded From UniProt	complete
involved_in	GO:0060395	SMAD protein signal transduction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1338027 MGI:MGI:88180 MGI:MGI:88182 MGI:MGI:95689 MGI:MGI:97359 PANTHER:PTN000218063 UniProtKB:O95390 UniProtKB:P12643 UniProtKB:P12644 UniProtKB:P18075 UniProtKB:P22004 UniProtKB:P43026 UniProtKB:P61812 UniProtKB:Q6KF10 UniProtKB:Q99988	P	Seeded From UniProt	complete
involved_in	GO:0048468	cell development	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103302 PANTHER:PTN000218063	P	Seeded From UniProt	complete
involved_in	GO:0043408	regulation of MAPK cascade	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107335 PANTHER:PTN000218063	P	Seeded From UniProt	complete
involved_in	GO:0042981	regulation of apoptotic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98726 PANTHER:PTN000218063	P	Seeded From UniProt	complete
involved_in	GO:0030509	BMP signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103302 MGI:MGI:88182 PANTHER:PTN000932177 UniProtKB:P18075 UniProtKB:P22004	P	Seeded From UniProt	complete
involved_in	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:107335 MGI:MGI:1338820 MGI:MGI:88182 MGI:MGI:95684 MGI:MGI:98727 PANTHER:PTN000218063 UniProtKB:O95393 UniProtKB:P01137 UniProtKB:P08476 UniProtKB:P12643 UniProtKB:P12644 UniProtKB:P18075 UniProtKB:P22003 UniProtKB:P22004 UniProtKB:Q6KF10 UniProtKB:Q7Z4P5 UniProtKB:Q96S42 UniProtKB:Q9UK05	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000490 MGI:MGI:103302 MGI:MGI:1338027 MGI:MGI:88177 MGI:MGI:88180 MGI:MGI:95691 MGI:MGI:98725 MGI:MGI:98726 PANTHER:PTN000218063 RGD:1305979 RGD:2211 RGD:2212 RGD:2213 RGD:2214 RGD:2912 RGD:2913 RGD:3115 RGD:3851 RGD:62074 RGD:620743 RGD:621512 RGD:69051 RGD:70491 UniProtKB:O14793 UniProtKB:O42220 UniProtKB:O95393 UniProtKB:P01137 UniProtKB:P12643 UniProtKB:P12644 UniProtKB:P18075 UniProtKB:P30371 UniProtKB:P61812 UniProtKB:Q96S42 UniProtKB:Q99988 WB:WBGene00000903	C	Seeded From UniProt	complete
enables	GO:0005160	transforming growth factor beta receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98725 PANTHER:PTN000218063 UniProtKB:P61812	F	Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000218063 UniProtKB:P08476 UniProtKB:P12644	F	Seeded From UniProt	complete
part_of	GO:0005623	cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0006879	C	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005125	P	Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P	Seeded From UniProt	complete
involved_in	GO:0071281	cellular response to iron ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0060586	multicellular organismal iron ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0060395	SMAD protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0060391	positive regulation of SMAD protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0045603	positive regulation of endothelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0030539	male genitalia development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0030509	BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0006879	cellular iron ion homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0001958	endochondral ossification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0001938	positive regulation of endothelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0001822	kidney development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0001654	eye development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0001649	osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P20722 ensembl:ENSMUSP00000126999	P	Seeded From UniProt	complete
involved_in	GO:0071773	cellular response to BMP stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
enables	GO:0070700	BMP receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	F	Seeded From UniProt	complete
involved_in	GO:0060395	SMAD protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	F	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0045669	positive regulation of osteoblast differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0032349	positive regulation of aldosterone biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0030509	BMP signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0030501	positive regulation of bone mineralization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
involved_in	GO:0003323	type B pancreatic cell development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P22004 ensembl:ENSP00000283147	P	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001839 InterPro:IPR017948	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0243	C	Seeded From UniProt	complete
involved_in	GO:2000872	positive regulation of progesterone secretion	PMID:21308853^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Diaz, FJ et al. (2011) Early avian follicular development is characterized by changes in transcripts involved in steroidogenesis, paracrine signaling and transcription. Mol. Reprod. Dev. 78 212-23 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21308853-2] Diaz, FJ et al. (2011) Early avian follicular development is characterized by changes in transcripts involved in steroidogenesis, paracrine signaling and transcription. Mol. Reprod. Dev. 78 212-23 PubMed GONUTS page

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CHICK:F1P4H2

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