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CHICK:BMP2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) BMP2 (synonyms: BMP-2)
Protein Name(s) Bone morphogenetic protein 2

BMP-2

External Links
UniProt Q90751
EMBL X75914
PIR I50607
UniGene Gga.3950
ProteinModelPortal Q90751
SMR Q90751
STRING 9031.ENSGALP00000014334
PaxDb Q90751
eggNOG NOG243555
HOVERGEN HBG004860
InParanoid Q90751
PhylomeDB Q90751
Proteomes UP000000539
GO GO:0005615
GO:0060317
GO:0051216
GO:0040007
GO:0001503
GO:0010718
Gene3D 2.10.90.10
InterPro IPR029034
IPR002405
IPR001839
IPR001111
IPR015615
IPR017948
PANTHER PTHR11848
Pfam PF00019
PF00688
PRINTS PR00669
SMART SM00204
SUPFAM SSF57501
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001503

ossification

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0892

P

Seeded From UniProt

complete

GO:0005125

cytokine activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002405

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

GO:0005615

extracellular space

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111
InterPro:IPR001839
InterPro:IPR017948

F

Seeded From UniProt

complete

GO:0008083

growth factor activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

Seeded From UniProt

complete

GO:0010718

positive regulation of epithelial to mesenchymal transition

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030154

cell differentiation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

Seeded From UniProt

complete

GO:0051216

cartilage development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0891

P

Seeded From UniProt

complete

GO:0060317

cardiac epithelial to mesenchymal transition

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

NOT

GO:0045893

positive regulation of transcription, DNA-templated

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0001503

ossification

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0892

P

complete

GO:0001649

osteoblast differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0001837

epithelial to mesenchymal transition

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0001934

positive regulation of protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0001938

positive regulation of endothelial cell proliferation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0003130

BMP signaling pathway involved in heart induction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0005125

cytokine activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0202

F

complete

GO:0005576

extracellular region

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002405

C

complete

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

complete

GO:0005576

extracellular region

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

C

complete

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

complete

GO:0005615

extracellular space

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0202

C

complete

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

F

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001839

F

complete

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017948

F

complete

GO:0008083

growth factor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0339

F

complete

GO:0008285

negative regulation of cell proliferation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0010628

positive regulation of gene expression

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0010718

positive regulation of epithelial to mesenchymal transition

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0010922

positive regulation of phosphatase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0019211

phosphatase activator activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

F

complete

GO:0021537

telencephalon development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0030154

cell differentiation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0221

P

complete

GO:0030501

positive regulation of bone mineralization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0030509

BMP signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0035051

cardiac cell differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0035630

bone mineralization involved in bone maturation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

complete

GO:0043065

positive regulation of apoptosis

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0045669

positive regulation of osteoblast differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0045778

positive regulation of ossification

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0045786

negative regulation of cell cycle

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0045893

positive regulation of transcription, DNA-dependent

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0046332

SMAD binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

F

complete

GO:0046982

protein heterodimerization activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

F

complete

GO:0048762

mesenchymal cell differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0051216

cartilage development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0891

P

complete

GO:0060317

cardiac epithelial to mesenchymal transition

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0060317

cardiac epithelial to mesenchymal transition

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0060389

pathway-restricted SMAD protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0060395

SMAD protein signal transduction

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0061036

positive regulation of cartilage development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

P

complete

GO:0070700

BMP receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000368104

F

complete

NOT

GO:0045893

positive regulation of transcription, DNA-dependent

PMID:18461597[1]

IMP: Inferred from Mutant Phenotype

P

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Sakabe, M et al. (2008) ROCK1 expression is regulated by TGFbeta3 and ALK2 during valvuloseptal endocardial cushion formation. Anat Rec (Hoboken) 291 845-57 PubMed GONUTS page