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CHICK:AVR2B
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | ACVR2B | |
Protein Name(s) | Activin receptor type-2B
Activin receptor type IIB ACTR-IIB | |
External Links | ||
UniProt | Q90670 | |
EMBL | U31223 | |
RefSeq | NP_989648.1 | |
UniGene | Gga.764 | |
ProteinModelPortal | Q90670 | |
SMR | Q90670 | |
STRING | 9031.ENSGALP00000030643 | |
PaxDb | Q90670 | |
GeneID | 374213 | |
KEGG | gga:374213 | |
CTD | 93 | |
eggNOG | COG0515 | |
HOGENOM | HOG000231495 | |
HOVERGEN | HBG054502 | |
InParanoid | Q90670 | |
KO | K13596 | |
PhylomeDB | Q90670 | |
NextBio | 20813717 | |
PRO | PR:Q90670 | |
Proteomes | UP000000539 | |
GO | GO:0016021 GO:0005524 GO:0046872 GO:0004702 GO:0004675 | |
InterPro | IPR011009 IPR000719 IPR008271 IPR000472 IPR000333 | |
PANTHER | PTHR23255 | |
Pfam | PF01064 PF00069 | |
PRINTS | PR00653 | |
SUPFAM | SSF56112 | |
PROSITE | PS50011 PS00108 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0009798 |
axis specification |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0048185 |
activin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0045178 |
basal part of cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0008283 |
cell population proliferation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
acts_on_population_of:(CL:0005014) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032924 |
activin receptor signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0061550 |
cranial ganglion development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(UBERON:0002058) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043525 |
positive regulation of neuron apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(UBERON:0002058) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048333 |
mesodermal cell differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
results_in_formation_of:(UBERON:0001135)|results_in_formation_of:(UBERON:0001134)|results_in_formation_of:(UBERON:0001133)|results_in_formation_of:(UBERON:0002328)|results_in_formation_of:(UBERON:0003062) |
Seeded From UniProt |
complete | ||
enables |
GO:0048185 |
activin binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:1901389 |
negative regulation of transforming growth factor beta activation |
DOI:10.1016/j.procbio.2011.10.027 |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048185 |
activin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:102806 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0048185 |
activin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:102806 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0048179 |
activin receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001147373 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0046332 |
SMAD binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98728 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0043235 |
receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000583675 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0034713 |
type I transforming growth factor beta receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001147373 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032924 |
activin receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001147373 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0019838 |
growth factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:102806 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007389 |
pattern specification process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1338938 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003716 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87911 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005026 |
transforming growth factor beta receptor activity, type II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001147373 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005024 |
transforming growth factor beta-activated receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98728 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007178 |
transmembrane receptor protein serine/threonine kinase signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Stern, CD et al. (1995) Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo. Dev. Biol. 172 192-205 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 McCullar, JS et al. (2010) Activin potentiates proliferation in mature avian auditory sensory epithelium. J. Neurosci. 30 478-90 PubMed GONUTS page
- ↑ 3.0 3.1 Koszinowski, S et al. (2015) Signaling via the transcriptionally regulated activin receptor 2B is a novel mediator of neuronal cell death during chicken ciliary ganglion development. Int. J. Dev. Neurosci. 41 98-104 PubMed GONUTS page
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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- Theropoda
- GO:0016740 ! transferase activity
- GO:0005026 ! transforming growth factor beta receptor activity, type II
- GO:0005024 ! transforming growth factor beta receptor activity
- GO:0007179 ! transforming growth factor beta receptor signaling pathway
- GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity
- GO:0034713 ! type I transforming growth factor beta receptor binding