CHICK:ANXA6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ANXA6 (synonyms: ANX6)
Protein Name(s)	Annexin A6 67 kDa calelectrin Annexin VI Annexin-6 Calphobindin-II CPB-II Chromobindin-20 Lipocortin VI P68 P70 Protein III
External Links
UniProt	P51901
EMBL	S67466
PIR	JC2029 S08990
RefSeq	NP_990061.1
UniGene	Gga.1099
ProteinModelPortal	P51901
SMR	P51901
STRING	9031.ENSGALP00000006938
PaxDb	P51901
PRIDE	P51901
GeneID	395481
KEGG	gga:395481
CTD	309
eggNOG	NOG267770
HOVERGEN	HBG061815
InParanoid	P51901
KO	K17094
PhylomeDB	P51901
NextBio	20815562
PRO	PR:P51901
Proteomes	UP000000539
GO	GO:0034704 GO:0042470 GO:0031982 GO:0005262 GO:0005509 GO:0005544 GO:0055074 GO:0070588 GO:0001755
Gene3D	1.10.220.10
InterPro	IPR001464 IPR018502 IPR018252 IPR002393
PANTHER	PTHR10502:SF19
Pfam	PF00191
PRINTS	PR00196 PR00202
SMART	SM00335
PROSITE	PS00223

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0001755	neural crest cell migration	PMID:22984583^[1]	ECO:0000315			P	Figures 3,7, and 9.	complete CACAO 6650
involved_in	GO:0001755	neural crest cell migration	PMID:22984583^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0097190	apoptotic signaling pathway	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88255 PANTHER:PTN002574762	P	Seeded From UniProt	complete
involved_in	GO:0070509	calcium ion import	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	P	Seeded From UniProt	complete
involved_in	GO:0051560	mitochondrial calcium ion homeostasis	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88255 PANTHER:PTN002574762	P	Seeded From UniProt	complete
involved_in	GO:0051283	negative regulation of sequestering of calcium ion	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	P	Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133	P	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
enables	GO:0048306	calcium-dependent protein binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133 UniProtKB:P79134	F	Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 RGD:621172	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133	F	Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
enables	GO:0035374	chondroitin sulfate binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
involved_in	GO:0031214	biomineral tissue development	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	P	Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133	F	Seeded From UniProt	complete
enables	GO:0015276	ligand-gated ion channel activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133	F	Seeded From UniProt	complete
enables	GO:0008201	heparin binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
involved_in	GO:0006937	regulation of muscle contraction	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88255 PANTHER:PTN002574762	P	Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	C	Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 RGD:621172 UniProtKB:P08133 UniProtKB:P79134	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P08133	F	Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
involved_in	GO:0003418	growth plate cartilage chondrocyte differentiation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	P	Seeded From UniProt	complete
enables	GO:0001786	phosphatidylserine binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P79134	F	Seeded From UniProt	complete
involved_in	GO:0001778	plasma membrane repair	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 ZFIN:ZDB-GENE-030707-3	P	Seeded From UniProt	complete
involved_in	GO:0001755	neural crest cell migration	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002574762 UniProtKB:P51901	P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0051560	C	Seeded From UniProt	complete
involved_in	GO:0034220	ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015276	P	Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005262	P	Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005262	P	Seeded From UniProt	complete
enables	GO:0005509	calcium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001464 InterPro:IPR002393 InterPro:IPR018252 InterPro:IPR018502 InterPro:IPR037104	F	Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001464 InterPro:IPR002393 InterPro:IPR018252 InterPro:IPR018502 InterPro:IPR037104	F	Seeded From UniProt	complete
involved_in	GO:0055074	calcium ion homeostasis	PMID:11696438^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0034704	calcium channel complex	PMID:11696438^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0031982	vesicle	PMID:11696438^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	PMID:11696438^[3]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0005544	calcium-dependent phospholipid binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0111	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0042470	melanosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0161	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Wu, CY & Taneyhill, LA (2012) Annexin a6 modulates chick cranial neural crest cell emigration. PLoS ONE 7 e44903 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Pfander, D et al. (2001) Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes. Am. J. Pathol. 159 1777-83 PubMed GONUTS page

[PMID:22984583-1] 1.0 ^1.1 Wu, CY & Taneyhill, LA (2012) Annexin a6 modulates chick cranial neural crest cell emigration. PLoS ONE 7 e44903 PubMed GONUTS page

[PMID:21873635-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 ^2.17 ^2.18 ^2.19 ^2.20 ^2.21 ^2.22 ^2.23 ^2.24 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11696438-3] 3.0 ^3.1 ^3.2 ^3.3 Pfander, D et al. (2001) Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes. Am. J. Pathol. 159 1777-83 PubMed GONUTS page

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CHICK:ANXA6

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