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CANFA:DUOX1

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Contents

Species (Taxon ID) Canis familiaris (Dog) (Canis lupus familiaris). ([1])
Gene Name(s) DUOX1 (synonyms: THOX1)
Protein Name(s) Dual oxidase 1

NADPH thyroid oxidase 1 Thyroid oxidase 1

External Links
EMBL AF230497
RefSeq NP_001003122.1
UniGene Cfa.3587
ProteinModelPortal Q9MZF4
PeroxiBase 3336
Ensembl ENSCAFT00000021757
GeneID 403720
KEGG cfa:403720
CTD 53905
eggNOG maNOG09856
GeneTree ENSGT00550000074350
HOVERGEN HBG080428
InParanoid Q9MZF4
OrthoDB EOG4VQ9ND
GO GO:0016324
GO:0016021
GO:0005509
GO:0009055
GO:0050660
GO:0020037
GO:0016174
GO:0050661
GO:0004601
GO:0042335
GO:0019221
GO:0042446
GO:0042744
GO:0051591
GO:0042554
InterPro IPR018248
IPR011992
IPR018247
IPR018249
IPR002048
IPR013112
IPR017927
IPR013121
IPR013130
IPR010255
IPR002007
IPR019791
IPR017938
Gene3D G3DSA:1.10.238.10
G3DSA:1.10.640.10
KO K13411
Pfam PF03098
PF00036
PF08022
PF01794
PF08030
PRINTS PR00457
SMART SM00054
SUPFAM SSF48113
SSF63380
PROSITE PS00018
PS50222
PS51384
PS50292

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004601

peroxidase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002007

F

Seeded From UniProt

GO:0004601

peroxidase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

F

Seeded From UniProt

GO:0004601

peroxidase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019791

F

Seeded From UniProt

GO:0004601

peroxidase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0575

F

Seeded From UniProt

GO:0005506

iron ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

Seeded From UniProt

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002048

F

Seeded From UniProt

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011992

F

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0006979

response to oxidative stress

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002007

P

Seeded From UniProt

GO:0006979

response to oxidative stress

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

P

Seeded From UniProt

GO:0006979

response to oxidative stress

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019791

P

Seeded From UniProt

GO:0009055

electron carrier activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0016174

NAD(P)H oxidase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.6.3.1

F

Seeded From UniProt

GO:0016174

NAD(P)H oxidase activity

PMID:10806195[1]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

GO:0016324

apical plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0015

C

Seeded From UniProt

GO:0016324

apical plasma membrane

PMID:10806195[1]

NAS: Non-traceable Author Statement

C

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013112

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013121

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017927

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017938

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded From UniProt

GO:0019221

cytokine-mediated signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000400283

P

Seeded From UniProt

GO:0019221

cytokine-mediated signaling pathway

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9NRD9

P

Seeded From UniProt

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002007

F

Seeded From UniProt

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

F

Seeded From UniProt

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019791

F

Seeded From UniProt

GO:0042335

cuticle development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000400283

P

Seeded From UniProt

GO:0042335

cuticle development

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9NRD9

P

Seeded From UniProt

GO:0042446

hormone biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0893

P

Seeded From UniProt

GO:0042554

superoxide anion generation

PMID:10806195[1]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

GO:0042744

hydrogen peroxide catabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0376

P

Seeded From UniProt

GO:0050660

flavin adenine dinucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013130

F

Seeded From UniProt

GO:0050661

NADP binding

PMID:10806195[1]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

GO:0051591

response to cAMP

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000400283

P

Seeded From UniProt

GO:0051591

response to cAMP

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q9NRD8

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002007

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013112

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013121

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017927

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017938

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019791

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 De Deken X et al. (2000) Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J Biol Chem 275: 23227-33 PubMed GONUTS page
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