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CANFA:APOE
Contents |
| Species (Taxon ID) | Canis familiaris (Dog) (Canis lupus familiaris). (9615) | |
| Gene Name(s) | APOE | |
| Protein Name(s) | Apolipoprotein E
Apo-E | |
| External Links | ||
| UniProt | P18649 | |
| PIR | A05310 C60940 | |
| ProteinModelPortal | P18649 | |
| STRING | P18649 | |
| eggNOG | maNOG14435 | |
| HOVERGEN | HBG010582 | |
| InParanoid | P18649 | |
| OrthoDB | EOG4GB76S | |
| GO | GO:0042627 GO:0034364 GO:0034361 GO:0001540 GO:0008201 GO:0006917 | |
| InterPro | IPR013326 IPR000074 | |
| Gene3D | G3DSA:1.20.120.20 | |
| Pfam | PF01442 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001540 |
beta-amyloid binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0001540 |
beta-amyloid binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded From UniProt |
||||
| GO:0001937 |
negative regulation of endothelial cell proliferation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0002021 |
response to dietary excess |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0005319 |
lipid transporter activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0005543 |
phospholipid binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005576 |
extracellular region |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0243 |
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
C |
Seeded From UniProt |
|||
| GO:0005615 |
extracellular space |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0006629 |
lipid metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0006641 |
triglyceride metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0006707 |
cholesterol catabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006869 |
lipid transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006869 |
lipid transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006874 |
cellular calcium ion homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0006898 |
receptor-mediated endocytosis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0006916 |
anti-apoptosis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0006917 |
induction of apoptosis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0006917 |
induction of apoptosis |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded From UniProt |
||||
| GO:0006979 |
response to oxidative stress |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0007263 |
nitric oxide mediated signal transduction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0008201 |
heparin binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008201 |
heparin binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0008203 |
cholesterol metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0008203 |
cholesterol metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0008289 |
lipid binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008289 |
lipid binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0010468 |
regulation of gene expression |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0010544 |
negative regulation of platelet activation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0010873 |
positive regulation of cholesterol esterification |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0010873 |
positive regulation of cholesterol esterification |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0010875 |
positive regulation of cholesterol efflux |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0016209 |
antioxidant activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0017127 |
cholesterol transporter activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
F |
Seeded From UniProt |
|||
| GO:0019934 |
cGMP-mediated signaling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0030195 |
negative regulation of blood coagulation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0030828 |
positive regulation of cGMP biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0032488 |
Cdc42 protein signal transduction |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0032805 |
positive regulation of low-density lipoprotein particle receptor catabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0033344 |
cholesterol efflux |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0033344 |
cholesterol efflux |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0033700 |
phospholipid efflux |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034361 |
very-low-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0034361 |
very-low-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0034362 |
low-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
C |
Seeded From UniProt |
|||
| GO:0034362 |
low-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0034363 |
intermediate-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0034364 |
high-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0034364 |
high-density lipoprotein particle |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0034372 |
very-low-density lipoprotein particle remodeling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0034372 |
very-low-density lipoprotein particle remodeling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034374 |
low-density lipoprotein particle remodeling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0034375 |
high-density lipoprotein particle remodeling |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034380 |
high-density lipoprotein particle assembly |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034382 |
chylomicron remnant clearance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034384 |
high-density lipoprotein particle clearance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0034447 |
very-low-density lipoprotein particle clearance |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0042157 |
lipoprotein metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0042157 |
lipoprotein metabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0042158 |
lipoprotein biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0042159 |
lipoprotein catabolic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0042311 |
vasodilation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0042627 |
chylomicron |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0042627 |
chylomicron |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
C |
Seeded From UniProt |
|||
| GO:0042632 |
cholesterol homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0042632 |
cholesterol homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0042802 |
identical protein binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0042803 |
protein homodimerization activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0043085 |
positive regulation of catalytic activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0043407 |
negative regulation of MAP kinase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0043537 |
negative regulation of blood vessel endothelial cell migration |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0043691 |
reverse cholesterol transport |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0045541 |
negative regulation of cholesterol biosynthetic process |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0046911 |
metal chelating activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0046982 |
protein heterodimerization activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0048156 |
tau protein binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0048844 |
artery morphogenesis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0050750 |
low-density lipoprotein particle receptor binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0051000 |
positive regulation of nitric-oxide synthase activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0051044 |
positive regulation of membrane protein ectodomain proteolysis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
P |
Seeded From UniProt |
|||
| GO:0051651 |
maintenance of location in cell |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0055088 |
lipid homeostasis |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
|||
| GO:0060228 |
phosphatidylcholine-sterol O-acyltransferase activator activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
F |
Seeded From UniProt |
|||
| GO:0060228 |
phosphatidylcholine-sterol O-acyltransferase activator activity |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0070326 |
very-low-density lipoprotein particle receptor binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000252486 |
F |
Seeded From UniProt |
|||
| GO:0071813 |
lipoprotein particle binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
F |
Seeded From UniProt |
|||
| GO:0072358 |
cardiovascular system development |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000133302 |
P |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
