GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
CANFA:AP3B1
Contents |
| Species (Taxon ID) | Canis familiaris (Dog) (Canis lupus familiaris). ([1]) | |
| Gene Name(s) | AP3B1 (synonyms: ADTB3A) | |
| Protein Name(s) | AP-3 complex subunit beta-1
Adapter-related protein complex 3 subunit beta-1 Adaptor protein complex AP-3 subunit beta-1 Beta-3A-adaptin Clathrin assembly protein complex 3 beta-1 large chain | |
| External Links | ||
| EMBL | AY221640 | |
| RefSeq | NP_001002974.1 | |
| UniGene | Cfa.169 | |
| ProteinModelPortal | Q7YRF1 | |
| STRING | Q7YRF1 | |
| GeneID | 403459 | |
| KEGG | cfa:403459 | |
| CTD | 8546 | |
| eggNOG | maNOG05565 | |
| GeneTree | ENSGT00530000063546 | |
| HOVERGEN | HBG050519 | |
| InParanoid | Q7YRF1 | |
| OrthoDB | EOG4H729X | |
| GO | GO:0030665 GO:0005794 GO:0030117 GO:0008565 GO:0006897 | |
| InterPro | IPR017108 IPR011989 IPR016024 IPR002553 | |
| Gene3D | G3DSA:1.25.10.10 | |
| KO | K12397 | |
| Pfam | PF01602 | |
| PIRSF | PIRSF037096 | |
| SUPFAM | SSF48371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005488 |
binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005794 |
Golgi apparatus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0132 |
C |
Seeded From UniProt |
|||
| GO:0006622 |
protein targeting to lysosome |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022196 |
P |
Seeded From UniProt |
|||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006886 |
intracellular protein transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006897 |
endocytosis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006897 |
endocytosis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007596 |
blood coagulation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022196 |
P |
Seeded From UniProt |
|||
| GO:0008565 |
protein transporter activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0015031 |
protein transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0015031 |
protein transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016192 |
vesicle-mediated transport |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0019882 |
antigen processing and presentation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022196 |
P |
Seeded From UniProt |
|||
| GO:0019903 |
protein phosphatase binding |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000255194 |
F |
Seeded From UniProt |
|||
| GO:0030117 |
membrane coat |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0030665 |
clathrin coated vesicle membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0071 |
C |
Seeded From UniProt |
|||
| GO:0031410 |
cytoplasmic vesicle |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0032438 |
melanosome organization |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSP00000255194 |
P |
Seeded From UniProt |
|||
| GO:0048007 |
antigen processing and presentation, exogenous lipid antigen via MHC class Ib |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022196 |
P |
Seeded From UniProt |
|||
|
Contributes to |
GO:0061082 |
myeloid leukocyte cytokine production |
IMP: Inferred from Mutant Phenotype |
P |
Figure 1 shows that a mutation of AP3B1 causes canine cyclic hematopoiesis, which results in reciprocal cycles of leukocyte (neutrophil and monocyte) production. |
complete | ||
| GO:0051138 |
positive regulation of NK T cell differentiation |
IEA: Inferred from Electronic Annotation |
Ensembl:ENSMUSP00000022196 |
P |
Seeded From UniProt |
|||
|
Contributes to |
GO:0043473 |
pigmentation |
IMP: Inferred from Mutant Phenotype |
P |
Table 1 shows that a mutation of AP3B1 causes canine cyclic hematopoiesis which results in gray coat color in dogs. |
complete | ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Benson KF et al. (2003) Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase. Nat Genet 35: 90-6 PubMed GONUTS page
