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CAEEL:MES4
Contents |
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | mes-4 | |
| Protein Name(s) | Histone-lysine N-methyltransferase mes-4
Maternal-effect sterile protein 4 | |
| External Links | ||
| UniProt | Q9NH52 | |
| EMBL | AF233290 AL021448 | |
| PIR | T26577 | |
| RefSeq | NP_506333.1 | |
| UniGene | Cel.6195 | |
| ProteinModelPortal | Q9NH52 | |
| SMR | Q9NH52 | |
| IntAct | Q9NH52 | |
| MINT | MINT-1040434 | |
| STRING | Q9NH52 | |
| EnsemblMetazoa | Y2H9A.1.1 Y2H9A.1.2 | |
| GeneID | 179824 | |
| KEGG | cel:Y2H9A.1 | |
| NMPDR | fig|6239.3.peg.20284 | |
| UCSC | Y2H9A.1 | |
| CTD | 43351 | |
| WormBase | Y2H9A.1 | |
| eggNOG | meNOG06667 | |
| GeneTree | EMGT00050000000655 | |
| InParanoid | Q9NH52 | |
| OMA | YAARLEC | |
| PhylomeDB | Q9NH52 | |
| NextBio | 907012 | |
| ArrayExpress | Q9NH52 | |
| GO | GO:0030849 GO:0000228 GO:0000805 GO:0046975 GO:0008270 GO:0008340 GO:0009792 GO:0018992 GO:0040027 GO:0016246 | |
| InterPro | IPR003616 IPR001214 IPR001841 | |
| KO | K07117 | |
| Pfam | PF00856 | |
| SMART | SM00508 SM00184 SM00317 | |
| PROSITE | PS50868 PS50280 PS01359 PS50016 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000003 |
reproduction |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00026633 |
P |
Seeded From UniProt |
|||
| GO:0000003 |
reproduction |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00027512 |
P |
Seeded From UniProt |
|||
| GO:0000228 |
nuclear chromosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0000805 |
X chromosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0191 |
C |
Seeded From UniProt |
|||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005694 |
chromosome |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0468 |
C |
Seeded From UniProt |
|||
| GO:0005694 |
chromosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0007275 |
multicellular organismal development |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0008168 |
methyltransferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0008340 |
determination of adult lifespan |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00084330 |
P |
Seeded From UniProt |
|||
| GO:0008340 |
determination of adult lifespan |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00084338 |
P |
Seeded From UniProt |
|||
| GO:0008340 |
determination of adult lifespan |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00084345 |
P |
Seeded From UniProt |
|||
| GO:0009792 |
embryo development ending in birth or egg hatching |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078967 |
P |
Seeded From UniProt |
|||
| GO:0009792 |
embryo development ending in birth or egg hatching |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00078970 |
P |
Seeded From UniProt |
|||
| GO:0010452 |
histone H3-K36 methylation |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00000483 |
P |
Seeded From UniProt |
|||
| GO:0016246 |
RNA interference |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00069199 |
P |
Seeded From UniProt |
|||
| GO:0016246 |
RNA interference |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00069200 |
P |
Seeded From UniProt |
|||
| GO:0016246 |
RNA interference |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081902 |
P |
Seeded From UniProt |
|||
| GO:0016458 |
gene silencing |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0016568 |
chromatin modification |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016571 |
histone methylation |
NAS: Non-traceable Author Statement |
|
P |
Seeded From UniProt |
|||
| GO:0016571 |
histone methylation |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0018024 |
histone-lysine N-methyltransferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0018992 |
germ-line sex determination |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0030849 |
autosome |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0032259 |
methylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0034968 |
histone lysine methylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081781 |
P |
Seeded From UniProt |
|||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081804 |
P |
Seeded From UniProt |
|||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081816 |
P |
Seeded From UniProt |
|||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081834 |
P |
Seeded From UniProt |
|||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081845 |
P |
Seeded From UniProt |
|||
| GO:0040027 |
negative regulation of vulval development |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00081864 |
P |
Seeded From UniProt |
|||
| GO:0042054 |
histone methyltransferase activity |
NAS: Non-traceable Author Statement |
|
F |
Seeded From UniProt |
|||
| GO:0042054 |
histone methyltransferase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046975 |
histone methyltransferase activity (H3-K36 specific) |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00000483 |
F |
Seeded From UniProt |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Fong Y et al. (2002) Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans. Science 296: 2235-8 PubMed GONUTS page
- ↑ 3.0 3.1 Rechtsteiner A et al. (2010) The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet 6: PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Curran SP et al. (2009) A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants. Nature 459: 1079-84 PubMed GONUTS page
- ↑ 5.0 5.1 Dudley NR et al. (2002) Using RNA interference to identify genes required for RNA interference. Proc Natl Acad Sci U S A 99: 4191-6 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Bender LB et al. (2006) MES-4: an autosome-associated histone methyltransferase that participates in silencing the X chromosomes in the C. elegans germ line. Development 133: 3907-17 PubMed GONUTS page
- ↑ 7.0 7.1 Kim JK et al. (2005) Functional genomic analysis of RNA interference in C. elegans. Science 308: 1164-7 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 8.3 8.4 8.5 8.6 Cui M et al. (2006) Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. PLoS Genet 2: e74 PubMed GONUTS page
