BOVIN:KPCA

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005886	plasma membrane		IEA: Inferred from Electronic Annotation		C	Source: UniProtKB-SubCell
	GO:0005524	ATP binding		IEA: Inferred from Electronic Annotation		F	Source: UniProtKB-KW
	GO:0005515	protein binding		IPI: Inferred from Physical Interaction		F	Source: UniProtKB
	GO:0008270	zinc ion binding		IEA: Inferred from Electronic Annotation		F	Source: InterPro
	GO:0005509	calcium ion binding	PMID:199593^[1]	IDA: Inferred from Direct Assay		F	Fig. 6. Ca2+ ions are required for phosphorylation.	complete
	GO:0016301	kinase activity	PMID:199594^[2]	IDA: Inferred from Direct Assay		F	Fig.4 and Fig. 5.	complete
	GO:0000166	nucleotide binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F
	GO:0004672	protein kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000719	F
	GO:0004672	protein kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017442	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000961	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002290	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008271	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017892	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0723	F
	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	F
	GO:0004697	protein kinase C activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014375	F
	GO:0004697	protein kinase C activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:2.7.11.13	F
	GO:0005515	protein binding	PMID:7844141^[3]	IPI: Inferred from Physical Interaction	UniProtKB:Q62083	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000719	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000961	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002290	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014375	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017441	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017442	F
	GO:0005524	ATP binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017892	F
	GO:0005524	ATP binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F
	GO:0005624	membrane fraction	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005634	nucleus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0539	C
	GO:0005634	nucleus	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0191	C
	GO:0005654	nucleoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005737	cytoplasm	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C
	GO:0005737	cytoplasm	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C
	GO:0005783	endoplasmic reticulum	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005829	cytosol	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005886	plasma membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C
	GO:0005886	plasma membrane	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	C
	GO:0005886	plasma membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0039	C
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000719	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000961	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002290	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008271	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014375	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017442	P
	GO:0006468	protein phosphorylation	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR017892	P
	GO:0008270	zinc ion binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014375	F
	GO:0016020	membrane	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C
	GO:0016301	kinase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0418	F
	GO:0016310	phosphorylation	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0418	P
	GO:0016740	transferase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F
	GO:0016772	transferase activity, transferring phosphorus-containing groups	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011009	F
	GO:0019899	enzyme binding	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	F
	GO:0035403	histone kinase activity (H3-T6 specific)	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	F
	GO:0035408	histone H3-T6 phosphorylation	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	P
	GO:0035556	intracellular signal transduction	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002219	P
	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	P
	GO:0046872	metal ion binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F
	GO:0070555	response to interleukin-1	GO_REF:0000019	IEA: Inferred from Electronic Annotation	Ensembl:ENSP00000408695	P
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Takai Y et al. (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J Biol Chem 252: 7603-9 PubMed GONUTS page
↑ Inoue M et al. (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. J Biol Chem 252: 7610-6 PubMed GONUTS page
↑ Staudinger J et al. (1995) PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol 128: 263-71 PubMed GONUTS page

[PMID:199593-0] Takai Y et al. (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J Biol Chem 252: 7603-9 PubMed GONUTS page

[PMID:199594-1] Inoue M et al. (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. J Biol Chem 252: 7610-6 PubMed GONUTS page

[PMID:7844141-2] Staudinger J et al. (1995) PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol 128: 263-71 PubMed GONUTS page

[1]

[2]

[3]

Species (Taxon ID)	Bos taurus (Bovine). (taxon:9913)
Gene Name(s)	PRKCA
Protein Name(s)	Protein kinase C alpha type PKC-A PKC-alpha
External Links
UniProt Identifier	KPCA_BOVIN
UniProt Accessions	P04409,
EMBL	M13973,
PIR	A00621,
RefSeq	NP_776860.1,
Pfam	PF00130, PF00168, PF00069, PF00433,

BOVIN:KPCA

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