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BOVIN:ITPR3

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Contents

Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) ITPR3
Protein Name(s) Inositol 1,4,5-trisphosphate receptor type 3

IP3 receptor isoform 3 IP3R 3 InsP3R3 Type 3 inositol 1,4,5-trisphosphate receptor Type 3 InsP3 receptor

External Links
UniProt Q8WN95
EMBL AF402601
IPI IPI00687393
RefSeq NP_776795.1
UniGene Bt.9025
ProteinModelPortal Q8WN95
SMR Q8WN95
STRING Q8WN95
PRIDE Q8WN95
GeneID 281879
KEGG bta:281879
CTD 3710
eggNOG maNOG09983
GeneTree ENSGT00600000084357
HOVERGEN HBG052158
InParanoid Q8WN95
GO GO:0005789
GO:0016021
GO:0030658
GO:0005220
GO:0005218
GO:0060402
InterPro IPR000699
IPR014821
IPR000493
IPR005821
IPR003608
IPR016093
IPR013662
IPR015925
KO K04960
PANTHER PTHR13715
Pfam PF08709
PF00520
PF02815
PF08454
PF01365
PRINTS PR00779
SMART SM00472
SUPFAM SSF82109
PROSITE PS50919

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0675

F

Seeded From UniProt

GO:0005216

ion channel activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

F

Seeded From UniProt

GO:0005216

ion channel activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0407

F

Seeded From UniProt

GO:0005218

intracellular ligand-gated calcium channel activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

F

Seeded From UniProt

GO:0005220

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000493

F

Seeded From UniProt

GO:0005220

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

F

Seeded From UniProt

GO:0005220

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

F

Seeded From UniProt

GO:0005262

calcium channel activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000699

F

Seeded From UniProt

GO:0005262

calcium channel activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0107

F

Seeded From UniProt

GO:0005783

endoplasmic reticulum

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000493

C

Seeded From UniProt

GO:0005783

endoplasmic reticulum

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0256

C

Seeded From UniProt

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0097

C

Seeded From UniProt

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

C

Seeded From UniProt

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded From UniProt

GO:0006811

ion transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

GO:0006811

ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

Seeded From UniProt

GO:0006816

calcium ion transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000493

P

Seeded From UniProt

GO:0006816

calcium ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0109

P

Seeded From UniProt

GO:0006816

calcium ion transport

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000493

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000699

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003608

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016093

C

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded From UniProt

GO:0030658

transport vesicle membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0245

C

Seeded From UniProt

GO:0031410

cytoplasmic vesicle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0968

C

Seeded From UniProt

GO:0048016

inositol phosphate-mediated signaling

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000493

P

Seeded From UniProt

GO:0048016

inositol phosphate-mediated signaling

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

P

Seeded From UniProt

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

GO:0060402

calcium ion transport into cytosol

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70227

P

Seeded From UniProt

GO:0070588

calcium ion transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000699

P

Seeded From UniProt

GO:0070588

calcium ion transmembrane transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0107

P

Seeded From UniProt

GO:0030141

secretory granule

PMID:11584008[1]

IDA: Inferred from Direct Assay

C

Fig. 2

complete

GO:0005791

rough endoplasmic reticulum

PMID:11584008[1]

IDA: Inferred from Direct Assay

C

The bovine adrenal medullary chromaffin cells were immunolabeled for type 1, 2, and 3 IP3R (10 nm) with each isoform-specific affinity-purified IP3R antibodies. As seen in figure 2C, the gold particles are also localized in the rough endoplasmic reticulum (rer as seen in the picture).

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Yoo SH et al. (2001) Localization of three types of the inositol 1,4,5-trisphosphate receptor/Ca(2+) channel in the secretory granules and coupling with the Ca(2+) storage proteins chromogranins A and B. J Biol Chem 276: 45806-12 PubMed GONUTS page
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