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BOVIN:GDF8

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Contents

Species (Taxon ID) Bos taurus (Bovine). ([1])
Gene Name(s) MSTN (synonyms: GDF8, MH)
Protein Name(s) Growth/differentiation factor 8

GDF-8 Myostatin

External Links
EMBL AF019761
AF019620
AF320998
AB076403
AY160688
AY850105
BC134563
IPI IPI00705829
RefSeq NP_001001525.1
UniGene Bt.605
ProteinModelPortal O18836
STRING O18836
Ensembl ENSBTAT00000015674
GeneID 281187
KEGG bta:281187
CTD 2660
eggNOG maNOG12997
HOVERGEN HBG000217
InParanoid O18836
OMA DLLMQVE
OrthoDB EOG4ZS93B
GO GO:0005615
GO:0005125
GO:0008083
GO:0040007
InterPro IPR015616
IPR001839
IPR001111
IPR015615
IPR017948
PANTHER PTHR11848:SF13
PTHR11848
Pfam PF00019
PF00688
SMART SM00204
PROSITE PS00250
PS51362

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005102

receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000027269

F

Seeded From UniProt

GO:0005102

receptor binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000260950

F

Seeded From UniProt

GO:0005125

cytokine activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0202

F

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

Seeded From UniProt

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

Seeded From UniProt

GO:0005615

extracellular space

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0202

C

Seeded From UniProt

GO:0007179

transforming growth factor beta receptor signaling pathway

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000027269

P

Seeded From UniProt

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

F

Seeded From UniProt

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001839

F

Seeded From UniProt

GO:0008083

growth factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017948

F

Seeded From UniProt

GO:0008083

growth factor activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0339

F

Seeded From UniProt

GO:0040007

growth

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

Seeded From UniProt

GO:0045893

positive regulation of transcription, DNA-dependent

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000260950

P

Seeded From UniProt

GO:0048632

negative regulation of skeletal muscle tissue growth

PMID:9314496[1]

IMP: Inferred from Mutant Phenotype

P

Figure 2; expression of non-functional allele in cattle

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kambadur R et al. (1997) Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res 7: 910-6 PubMed GONUTS page
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