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BACSU:SFP

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Contents

Species (Taxon ID) Bacillus subtilis. ([1])
Gene Name(s) sfp (synonyms: lpa-8)
Protein Name(s) 4'-phosphopantetheinyl transferase sfp

Surfactin synthase-activating enzyme

External Links
EMBL X63158
X65610
L17438
X70356
D50562
AL009126
PIR S20463
PDB 1QR0
2GE0
2GE1
PDBsum 1QR0
2GE0
2GE1
ProteinModelPortal P39135
SMR P39135
NMPDR fig|224308.1.peg.358
GenoList BSU03570
HOGENOM HBG343452
BioCyc MetaCyc:MONOMER-13919
GO GO:0008897
GO:0000287
GO:0017000
GO:0006633
GO:0009059
InterPro IPR008278
IPR004568
Gene3D G3DSA:3.90.470.20
Pfam PF01648
SUPFAM SSF56214
TIGRFAMs TIGR00556

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000287

magnesium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004568

F

Seeded From UniProt

GO:0000287

magnesium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008278

F

Seeded From UniProt

GO:0006633

fatty acid biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004568

P

Seeded From UniProt

GO:0008897

holo-(acyl-carrier-protein) synthase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004568

F

Seeded From UniProt

GO:0008897

holo-(acyl-carrier-protein) synthase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008278

F

Seeded From UniProt

GO:0009059

macromolecule biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008278

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0017000

antibiotic biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0045

P

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded From UniProt

GO:0009059

macromolecule biosynthetic process

PMID:11572999[1]

IMP: Inferred from Mutant Phenotype

P

Surfactants are known to be important for the erection of aerial hyphae in fungi and the streptomycetes, caused at least in part by their ability to lower the surface tension of water..

A mutant (sfp) lacking the phosphopantetheinyltransferase that activates the nonribosomal peptide synthetase that produces surfactin formed thick but completely flat pellicles (Fig. 4A). Similarly, sfp mutant colonies were flat and small, spreading very little on the agar surface (Fig. 4 B and C). Low-magnification microscopy revealed that these mutant colonies did form projecting columns, but these grew laterally and eventually fused with each other (Fig. 4C), leading to small colonies lacking aerial structures.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Branda SS et al. (2001) Fruiting body formation by Bacillus subtilis. Proc Natl Acad Sci U S A 98: 11621-6 PubMed GONUTS page
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