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BACAN:Q81JD7

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Species (Taxon ID) Bacillus anthracis. (1392)
Gene Name(s) bclA (ECO:0000313 with EMBL:CAD56869.1)
Protein Name(s) BclA protein (ECO:0000313 with EMBL:CAD56869.1)

Spore surface glycoprotein BclA (ECO:0000313 with EMBL:AAP25181.1) Uncharacterized protein (ECO:0000313 with EMBL:AAT30311.1)

External Links
UniProt Q81JD7
EMBL AE016879
AE017334
AB281483
AJ516936
RefSeq NP_843695.1
YP_017836.1
PDB 2R6Q
3TWI
3TYJ
PDBsum 2R6Q
3TWI
3TYJ
SMR Q81JD7
IntAct Q81JD7
STRING 198094.BA_1222
EnsemblBacteria AAP25181
AAT30311
GeneID 1084744
2814858
KEGG ban:BA_1222
bar:GBAA_1222
PATRIC 18780046
HOGENOM HOG000085653
OMA HAQFIER
OrthoDB EOG6HTP1D
BioCyc BANT261594:GJ7F-1260-MONOMER
EvolutionaryTrace Q81JD7
Proteomes UP000000427
UP000000594
GO GO:0050764
Gene3D 2.60.120.40
InterPro IPR008160
IPR008983
Pfam PF01391

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043934

sporulation

  • The co-dependence of BxpB/ExsFA and BclA for proper incorporation into the exosporium of Bacillus anthracis.
  • Thompson BM, Hsieh HY, Spreng KA, Stewart GC.

ECO:0000314

P

Mutagenesis used to show that BclA plays a factor in the positioning and stabilization of the protein

Missing: reference

GO:0006958

complement activation, classical pathway

PMID:22442442[1]

ECO:0000314

P

figure 5 demonstrated that the presence of BclA protein significantly enhance the C3 deposition on the spore surface; C3 is a critical components in classical complement pathway

complete
CACAO 4094

GO:0050764

regulation of phagocytosis

PMID:22442442[1]

ECO:0000314

P

Figure 7 "suggested BclA is required for complement-mediated phagocytosis of spores"

complete
CACAO 4095

involved_in

GO:0050764

regulation of phagocytosis

PMID:22442442[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gu, C et al. (2012) Activation of the classical complement pathway by Bacillus anthracis is the primary mechanism for spore phagocytosis and involves the spore surface protein BclA. J. Immunol. 188 4421-31 PubMed GONUTS page