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AGRT5:Q7D233

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Species (Taxon ID) Agrobacterium tumefaciens (strain C58 / ATCC 33970). (176299)
Gene Name(s) irr (ECO:0000313 with EMBL:AAK85974.2)
Protein Name(s) Transcriptional regulator, Fur family (ECO:0000313 with EMBL:AAK85974.2)
External Links
UniProt Q7D233
EMBL AE007869
RefSeq NP_353189.2
ProteinModelPortal Q7D233
STRING 176299.Atu0153
EnsemblBacteria AAK85974
GeneID 1132191
KEGG atu:Atu0153
PATRIC 20809984
eggNOG COG0735
HOGENOM HOG000014145
KO K09826
OMA TNTSDHY
OrthoDB EOG6J48SS
BioCyc AGRO:ATU0153-MONOMER
Proteomes UP000000813
GO GO:0003677
GO:0003700
Gene3D 1.10.10.10
InterPro IPR002481
IPR011991
Pfam PF01475

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:2000143

negative regulation of DNA-dependent transcription, initiation

PMID:22817265[1]

ECO:0000315

P

When looking at Figure 2 it is evident that the more mutations in the irr gene that impact Irr protein function have a negative impact on its ability to repress a mbfA-lacZ reporter gene. According to the paper a double mutation will have a small defect but a triple mutation will cause a large defect in the repressor function.

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002481

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002481

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000481764

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000481764

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bhubhanil, S et al. (2012) Identification of amino acid residues important for the function of Agrobacterium tumefaciens Irr protein. FEMS Microbiol. Lett. 335 68-77 PubMed GONUTS page